Science Fiction
Dictionary
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
 |
Fantastic Voyage Of Self-assembling Peptide Nanofibers
In the 1966 science fiction movie Fantastic Voyage, researchers miniaturize a delivery mechanism and inject it into a human body. In a modern day sequel, Harvard Medical School researchers have used injectable self-assembling peptide nanofibers loaded with the pro-survival factor PDGF-BB to protect rat hearts from injury and subsequent heart failure. Their study will appear in the January 2006 issue of the Journal of Clinical Investigation.
(1966 Fantastic Voyage)
Narrowed or blocked blood vessels are unable to deliver sufficient levels of oxygen to cardiomyocytes, which results in cardiomyocyte death, loss of the middle layer of the heart wall (the myocardium), and ultimately, heart failure. Therefore, therapies that protect cardiomyocytes from death may help prevent heart failure.In the current study, Richard Lee and colleagues show that PDGF-BB has a direct pro-survival effect on cardiomyocytes. The authors went on to design a strategy in which short, self-assembling peptide nanofibers bind this pro-survival growth factor and, following injection into rat myocardium, facilitated prolonged and controlled delivery of PDGF-BB to the infarcted heart for up to 14 days. This strategy protected cardiomyocytes from injury, reduced infarct size, and preserved cardiac function. This effect could not be achieved by injecting nanofibers or PDGF-BB alone.
In a previous paper, Dr. Lee and his team demonstrated that self-assembling peptide nanofibers can be injected, and that the resulting nanofiber microenvironment can be seen.
If you are interested in this topic, you might also be interested in an Artist's View Of Medical Nanorobots. Read more at ZDNet, the press release, and Molecular Cardiology. And thanks to Fred Kiesche for pointing this one out.
Scroll down for more stories in the same category. (Story submitted 12/20/2005)
Follow this kind of news @Technovelgy.| Email | RSS | Blog It | Stumble | del.icio.us | Digg | Reddit |
Would
you like to contribute a story tip?
It's easy:
Get the URL of the story, and the related sf author, and add
it here.
Comment/Join discussion ( 0 )
Related News Stories - (" Medical ")
Brain Implant Is Able To Capture Your Inner Dialogue
'So you see, you can hide nothing from me.'
'Pregnancy Humanoids' From China Replace Moms
'A great many of these synthetic babies were made...' - David H. Keller, 1928.
Bacteria Turns Plastic Into Pain Relief? That Gives Me An Idea.
'I guess there's nobody round this table who doesn't have a Crosswell [tapeworm] working for him in the small intestine.'
Heart Patches Grown In The Lab Repair Hearts
I'm hoping that this procedure becomes a normal part of medical practice!
Technovelgy (that's tech-novel-gee!) is devoted to the creative science inventions and ideas of sf authors. Look for the Invention Category that interests you, the Glossary, the Invention Timeline, or see what's New.
Science Fiction
Timeline
1600-1899
1900-1939
1940's 1950's
1960's 1970's
1980's 1990's
2000's 2010's
Current News
RoboBallet The Dance Of Cooperative Robots
'...an integrated seven-unit robot team.'
Chrysalis Generation Ship to Alpha Centauri
'This was their world, their planet —
this swift-traveling, yet seemingly moveless vessel.'
Alexa+ And Its AI Brain Improvements
'What's it do?' he asked. 'It amuses.'
Does CloneRobotics Offer A True Android?
Is this What Little Girls Are Made Of?
Brain Implant Is Able To Capture Your Inner Dialogue
'So you see, you can hide nothing from me.'
Are AIs Going Rogue Like Hal 9000
'I know that you and Frank were planning to disconnect me...'
Animated Tumblebugs On Astounding Cover!
'Gaines and Harvey mounted tumblebugs, and kept abreast of the Cadet Captain...'
LingYuan Vehicle Roof Drones Now Available, ala Blade Runner 2049
Accompanied by a small selection of similar ideas from science fiction.
China Steals Strato Airship Design From Google App Engine
'...war-balloons, or, as it would be more correct to call them, navigable aerostats.'
The First Space Warship For Space Force
'Each of the electrical ships carried about twenty men...'
Biohybrid Jellyfish Explore The Ocean
As predicted, and detailed, by science fiction writers!
Should AIs and AI Robots Demand Rights?
'This robot is a creature... It is a manlike being. Therefore, like any other talking, thinking man, he is entitled to a court trial!'
Robot Learns Human Tool Usage By Imitation Learning
'I got one of those new electronic cameras...'
Companion Caregiver ChatGPT Dolls
'Every Artificial Friend is unique, right?'
'Pregnancy Humanoids' From China Replace Moms
'A great many of these synthetic babies were made...'
Man Builds 200 Foot Basement Firing Range
'The basement was huge... carved deep into the rock.'
