Science Fiction
Dictionary
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
 |
AICAR Exercise In A Pill
AICAR is exercise in a pill for mice; the drug appears to give the couch potato mouse much more stamina.
(Ronald Evans shows vial of exercise in a pill)
The drug appeared to change the physical composition of muscle, essentially transforming the tissue from sugar-burning fast-twitch fibers to fat-burning slow-twitch ones, the same change that occurs in distance runners and cyclists through training, according to research released Thursday."You're getting the benefits of exercise without having to do any work," said David Mangelsdorf, a pharmacologist at University of Texas Southwestern Medical Center in Dallas, who was not connected with the research.
Ronald Evans, the lead researcher and a molecular physiologist at the Salk Institute in La Jolla, has been contacted by many athletes in spite of the fact that AICAR does not appear to work in humans at the kinds of doses that mice receive. Evans has already turned over detection protocols to the World Anti-Doping Agency in Montreal just in case.
When sedentary mice were fed the drug daily for four weeks, they were able to run an average of 1,795 feet on a treadmill, 44% farther than mice that had received a placebo.
Mice seem to get all of the great science for strength and stamina; see transgenic mice for details.
Update 05-Aug-2008: As BajaB points out, the Han in Philip Nowlan's Armageddon 2419 A.D. had figured out how to do this:
Yet in spite of the fact that they had to bear their own full weight at all times, they were physically far inferior to the Americans. They lived lives of physical inertia, having machinery of every description for the performance of all labor, and convenient conveyances for any movement of more than a few steps.Even from the twisted wreckage of this ship I could see that seats, chairs and couches played an extremely important part in their scheme of existence.
But none of the bodies were overweight. They seemed have been the bodies of men in good health, but muscularly much underdeveloped. Wilma explained to me that they had mastered the science of gland control, and of course dietetics, to the point where men and women among them not uncommonly reached the age of a hundred years with arteries and general health in splendid condition.
End update.
From AICAR: Scientists say they've put exercise in a pill; thanks to Moira for the tip on this story, and of course BajaB for the pointer to the reference.
Scroll down for more stories in the same category. (Story submitted 8/2/2008)
Follow this kind of news @Technovelgy.| Email | RSS | Blog It | Stumble | del.icio.us | Digg | Reddit |
Would
you like to contribute a story tip?
It's easy:
Get the URL of the story, and the related sf author, and add
it here.
Comment/Join discussion ( 2 )
Related News Stories - (" Medical ")
Drug To Regenerate Teeth In Humans
'We want to do something to help those who are suffering from tooth loss or absence,' said lead researcher Katsu Takahashi.
Illustrating Classic Heinlein With AI
'Stasis, cold sleep, hibernation, hypothermia, reduced metabolism, call it what you will - the logistics-medicine research teams had found a way to stack people like cordwood and use them when needed.' - Robert Heinlein, 1956
Brainoware Reservoir Computation Of Biological Neural Networks
'Head cheese. Cultured brains on a slab.' - Peter Watts, 1999.
Forward CarePod The AI Doctor's Office
'It's an old model,' Rawlins said. 'I'm not sure what to do.'
Technovelgy (that's tech-novel-gee!) is devoted to the creative science inventions and ideas of sf authors. Look for the Invention Category that interests you, the Glossary, the Invention Timeline, or see what's New.
Science Fiction
Timeline
1600-1899
1900-1939
1940's 1950's
1960's 1970's
1980's 1990's
2000's 2010's
Current News
Cognify - A Prison Of The Mind We've Seen Before In SF
'So I serve a hundred years in one day...'
Robot With Human Brain Organoid - 'A Thrilling Story Of Mechanistic Progress'
'A human brain snugly encased in a transparent skull-shaped receptacle.'
Goodness Gracious Me! Google Tries Face Recognition Security
'The actuating mechanism that should have operated by the imprint of her image on the telephoto cell...'
With Mycotecture, We'll Just Grow The Space Habitats We Need
'The only real cost was in the plastic balloon that guided the growth of the coral and enclosed the coral's special air-borne food.'
Can A Swarm Of Deadly Drones Take Out An Aircraft Carrier?
'The border was defended by... a swarm of quasi-independent aerostats.'
WiFi and AI Team Up To See Through Walls
'The pitiless M rays pierced Earth and steel and densest concrete as if they were so much transparent glass...'
Climate Engineering In California Could Make Europe's Heat Waves Worse
'Pina2bo would have to operate full blast for many years to put as much SO2 into the stratosphere as its namesake had done in a few minutes.'
Optimus Robot Will Be A Good Nanny, Says Musk
'Nanny is different,' Tom Fields murmured... 'she's not like a machine. She's like a person.'
ESA To Build Moon Bases Brick By Printed LEGO Brick
'We made a crude , small cell and were delighted - and, I admit, somewhat surprised - to find it worked.'
Does The Shortage Of Human Inputs Limit AI Development?
'...we've promised him a generous pension from the royalties.'
Textiles That Harvest Energy And Store It
'The clothes and jewelery drew their tiny power requirements from her movements.'
LORIS Passive-Gripper Climbing Robot
'At the end of each appendage's eight fingers there are tinier appendages...'
Neuroplatform Human Brain Organoid Bioprocessor Uses Less Electricity
'Cultured brains on a slab.'
Drug To Regenerate Teeth In Humans
'We want to do something to help those who are suffering from tooth loss or absence,' said lead researcher Katsu Takahashi.
Coin-Sized Nuclear Battery Good For 100 Years
'...power pack the size of a pea.'
Live Stream With Meta-Ban Multimodal Smart Glasses
'...the bug-eyed, opaque gape of her True-Vu lenses.'
