Science Fiction
Dictionary
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
 |
Limb Regeneration Grows Closer
How does limb regeneration work in animals like salamanders? If you cut off their tails, they are able to completely recreate the missing limb, including bones, muscle, skin, blood vessels and nerves.
However, new research published in Nature seems to indicate that the mechanism is simpler than previously supposed. An experiment designed by Elly Tanaka at the Center for Regenerative Therapies, in Dresden, Germany employed a new method for tracking what happens in the axolotl when it is injured.
In salamanders, new tissues come from a tumorlike mass of cells that forms at the site of the injury, called the blastema. Until now, most scientists thought that the blastema contained a population of stem cells that had become pluripotent--capable of giving rise to all the needed tissues.
( Schwann cells are shown here in a salamander limb )
The researchers first created transgenic axolotls that carried green fluorescent protein (GFP) in their entire bodies. When the animals were still embryos, the researchers removed a piece of tissue from the limb region of the transgenic animals and transplanted the tissue into the same location in nontransgenic axolotls. The transplants were incorporated into the growing body as normal cells, and when the limb of the transplant recipients were then severed, the researchers could track the fate of the fluorescent cells as the limb regrew.The researchers used this method to track the fate of cells of the inner and outer skin, muscles, and cartilage, as well as Schwann cells, which insulate nerve fibers. They found that, contrary to previous evidence, muscle cells at the amputation site only become muscle cells in the new limb. Other cell types also stuck to their previous identities; the only exception, Tanaka says, is that cells of the inner layers of skin and cartilage seem to be able to transform into one another.
Frank Herbert wrote about the idea of limb regeneration in his appropriately named "axolotl tank" from his 1969 novel Dune Messiah:
"Even in defeat," Edric said, "your father's Sardaukar did not abandon wisdom. Let us suppose a wise Sardaukar commander recognized the swordmaster in a corpse his men had slain. What then? There exist uses for such flesh and training . . . if one acts swiftly...""A Tleilaxu ghola," Irulan whispered...
...Edric said. "...let us assume that our wise Sardaukar commander had Idaho's corpse preserved for the axolotl tanks.
(Read more about Herbert's axolotl tank)
From MIT's Technology Review.
Scroll down for more stories in the same category. (Story submitted 7/3/2009)
Follow this kind of news @Technovelgy.| Email | RSS | Blog It | Stumble | del.icio.us | Digg | Reddit |
Would
you like to contribute a story tip?
It's easy:
Get the URL of the story, and the related sf author, and add
it here.
Comment/Join discussion ( 5 )
Related News Stories - (" Medical ")
Heart Patches Grown In The Lab Repair Hearts
I'm hoping that this procedure becomes a normal part of medical practice!
Pixel Watch 'Loss of Pulse Detection' And Philip K. Dick
'He carried on his person a triggering mechanism sensitive to his heartbeat.' - Philip K. Dick, 1965.
ErythroMer Artificial Blood
'My chemists are all working on the preparation of the artificial blood.' - Dr. David H. Keller, M.D.
MouthPad Supports Head And Tongue Tracking
'The operation that had transformed half his body... had located the control switchboard in his teeth.'- Alfred Bester, 1956.
Technovelgy (that's tech-novel-gee!) is devoted to the creative science inventions and ideas of sf authors. Look for the Invention Category that interests you, the Glossary, the Invention Timeline, or see what's New.
Science Fiction
Timeline
1600-1899
1900-1939
1940's 1950's
1960's 1970's
1980's 1990's
2000's 2010's
Current News
Robot Hand Creeps Along, Separate From It's Owner
'The crawling... object was V-Stephen's surgeon-hand...'
Taikonauts Exercise In China's Tiangong Space Station
'Joe got out the gravity-simulator harnesses...'
Korean Exoskeleton Suit F1 Helps You Put It On
'Better late than never.'
Have AI Researchers Given Up On 'Bio-Babies'?
'You couldn't have the capstone without the pyramid to hold it up.'
Bunker Busters and Bore-Pellets
'The first revelation of the new Soviet bore-pellets.'
'Spikeless' Brand Swizzle Stick Detects Spiked Drinks
'the unobtrusive inspections with tiny remote-cast snoopers...'
Heart Patches Grown In The Lab Repair Hearts
I'm hoping that this procedure becomes a normal part of medical practice!
Humanoid Robots Spotted In Homes Performing Household Chores
'... nothing was perfected until M. Pantalon announced the completion of his automatic valet.'
Musk Proposes Sites For Martian Cities
'...its streets were of remarkable width, with few or no buildings so high as mosques, churches, State-offices, or palaces in Tellurian cities.'
Bambot Open Source Cheap Delivery Robot
'Not since the time he rewired the delivery robot...'
Robot Collective Acts Like A Smart Material
'...it was all composed of tiny, identical cubes, carefully laid to form a tilelike surface.'
Vipera Electric Skis From Frigid Dynamics
'JOAN strapped on her power-skis...'
Pixel Watch 'Loss of Pulse Detection' And Philip K. Dick
'He carried on his person a triggering mechanism sensitive to his heartbeat.'
Nuclear Plant Restarted To Power AI To Feed Us Dreams
'...Anything was possible in my imaginary environment.'
SpaceX's Starman Tesla Roadster In Space
'Somewhere in space, a chrome and blue automobile raced the green light of Earth.'
Pivotal Blackfly Electric Aircraft Lifts And Hovers
'That explains how it was so easy for me to remain motionless in midair...'
