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"The answer to the problem of information overload on the Net is reputations… engineer a system called a reputation server."
- Neal Stephenson

Anadrenalin  
  Has the opposite effect of adrenalin.  

He even discovered a couple of new ones, especially one he calls "anadrenalin", because it has just the opposite effect of adrenalin. Instead of stimulating the heard violently, it retards the heart and the whole neural system to infinitesimal activity.
Technovelgy from A Race Through Time, by Donald Wandrei.
Published by Astounding Science Fiction in 1933
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