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"I love that computer science has made mathematics into something like an experimental science. I was never all that good at proving things, but I love doing computer experiments."
- Rudy Rucker

Replacement of Brain with Computer  
  Removal of the brain of an ordinary man, and installation of a calculating machine.  

The earliest description of this idea in science fiction.

"My endeavors in mechanism had resulted in a machine which went far beyond Babbage's in its powers of calculation. Given the data, there was no limit to the possibilities in this direction. Babbage's cogwheels and pinions calculated logarithms, calculated an eclipse. It was fed with figures, and produced results in figures. Now, the relations of cause and effect are as fixed and unalterable as the laws of arithmetic. Logic is, or should be, as exact a science as mathematics. My new machine was fed with facts, and produced conclusions. In short, it reasoned; and the results of its reasoning were always true, while the results of human reasoning are often, if not always, false. The source of error in human logic is what the philosophers call the `personal equation.' My machine eliminated the personal equation; it proceeded from cause to effect, from premise to conclusion, with steady precision. The human intellect is fallible; my machine was, and is, infallible in its processes.

"Again, physiology and anatomy had taught me the fallacy of the medical superstition which holds the gray matter of the brain and the vital principle to be inseparable. I had seen men living with pistol balls imbedded in the medulla oblongata. I had seen the hemispheres and the cerebellum removed from the crania of birds and small animals, and yet they did not die. I believed that, though the brain were to be removed from a human skull, the subject would not die, although he would certainly be divested of the intelligence which governed all save the purely involuntary actions of his body.

"Once more: a profound study of history from the sociological point of view, and a not inconsiderable practical experience of human nature, had convinced me that the greatest geniuses that ever existed were on a plane not so very far removed above the level of average intellect. The grandest peaks in my native country, those which all the world knows by name, tower only a few hundred feet above the countless unnamed peaks that surround them. Napoleon Bonaparte towered only a little over the ablest men around him. Yet that little was everything, and he overran Europe. A man who surpassed Napoleon, as Napoleon surpassed Murat, in the mental qualities which transmute thought into fact, would have made himself master of the whole world.

"Now, to fuse these three propositions into one: suppose that I take a man, and, by removing the brain that enshrines all the errors and failures of his ancestors away back to the origin of the race, remove all sources of weakness in his future career. Suppose, that in place of the fallible intellect which I have removed, I endow him with an artificial intellect that operates with the certainty of universal laws. Suppose that I launch this superior being, who reasons truly, into the burly burly of his inferiors, who reason falsely, and await the inevitable result with the tranquillity of a philosopher. "Monsieur, you have my secret. That is precisely what I have done. In Moscow, where my friend Dr. Duchat had charge of the new institution of St. Vasili for hopeless idiots, I found a boy of eleven whom they called Stépan Borovitch. Since he was born, he had not seen, heard, spoken or thought. Nature had granted him, it was believed, a fraction of the sense of smell, and perhaps a fraction of the sense of taste, but of even this there was no positive ascertainment. Nature had walled in his soul most effectually. Occasional inarticulate murmurings, and an incessant knitting and kneading of the fingers were his only manifestations of energy. On bright days they would place him in a little rocking-chair, in some spot where the sun fell warm, and he would rock to and fro for hours, working his slender fingers and mumbling forth his satisfaction at the warmth in the plaintive and unvarying refrain of idiocy. The boy was thus situated when I first saw him.

Technovelgy from The Ableist Man in the World, by Edward Page Mitchell.
Published by Not Known in 1879
Additional resources -

Compare to the clockwork man from The Clockwork Man (1923) by E.V. Odle.

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Additional resources:
  More Ideas and Technology from The Ableist Man in the World
  More Ideas and Technology by Edward Page Mitchell
  Tech news articles related to The Ableist Man in the World
  Tech news articles related to works by Edward Page Mitchell

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