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"...in fifty years, do you believe that people will be recognizably human?"
- Greg Bear

Vivo-Gel  
  Semi-living material.  

Very early use of this somewhat disturbing idea.

The small yellow-faced man with the deep-set amber eyes drew a good number of amused and curious stares during the two days he was registered at the Old Lycannese Hotel.

He expected nothing else. Even in such sophisticated and galactic-minded surroundings, his appearance was fantastic to a rather indecent degree. The hairless dome of his head sloped down comically into a rounded snout. He was noseless and apparently earless, and in animated moments his naked yellow scalp would twitch vigorously like the flanks of some vermin-bitten beast.

This curiosity-distracting effect, the yellow-faced man considered, as he strolled across the ground-floor lobby, was almost as satisfactory when it was applied to those who had reason to take a much sharper practical interest in any stranger!

Stripping the vivo-gel masks carefully from his head and hands, he dropped the frenziedly twitching half-alive stuff into the depository beside his seat where the car's jets would destroy it.

Technovelgy from Agent of Vega, by James Schmitz.
Published by Astounding Science-Fiction in 1949
Additional resources -

Compare to Frank Herbert's uniflesh from The Dosadi Experiment (1977).

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Additional resources:
  More Ideas and Technology from Agent of Vega
  More Ideas and Technology by James Schmitz
  Tech news articles related to Agent of Vega
  Tech news articles related to works by James Schmitz

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