Comments on Bone Transplant Grown In Patient's Abdomen From Stem Cells
This is a remarkable result; let's hope that stem cell research is allowed to proceed in this country as well. (Read
the complete story)
|"Your comment on the article sounds political, but is misplaced; This science is based on ADULT stem cell research, which both the US government AND most EMBRYO stem cell research opponents AGREE is a good thing.
The argument is not over this, but over EMBRYONIC stem cell research, which unlike adult stem cell research has been mostly a scientific dry hole. Adult stem cell research has been great: Embryonic stem cell research is simply a political football for the abortion providers, has moral issues attached to it, and has not produced anywhere near the same results.
I don't care if you defend it, but get it straight about what kind of research is working, and who supports it or not.
(anonymous 2/4/2008 4:44:49 PM)
|"You failed to mention the country this happened in, which is Finland of course.
(the city alone should be enough to know the country, but since the city mentioned wasn't the capital, I thought best to clear it up for some geographically challenged people ;))"
(I thought Europe was a country 2/4/2008 10:23:30 PM)
|"Your comment unfortunately perpetuates the incorrect notion that stem cell research is not allowed in the USA. As the first commenter points out, adult stem cell research, like the research described in this article, is not even controversial. Embryonic stem cell research is also allowed in the USA, though it has shown much less promise and therefore attracts less private funding. Embryonic stem cell research is also eligible for federal funding in the USA, thanks to President Bush -- it was not eligible for such funding until 2001 -- as long as it makes use of stem cell lines that started before August of that year. And the passage of time has only made the use of embryonic stem cells less necessary, since in 2007 researchers found ways of creating the equivalent of embryonic stem cells from adult stem cells."
(Mark 2/5/2008 9:10:45 AM)
|"Regarding the comment made above by anon., I think I was clear that the stem cells used were adult cells cultured from the patient's own body fat. Regarding the larger issues of using the two types of stem cells, it seems clear that stem cell research was oversold; people were lead to believe that a magic cure was right in front of researchers. In fact, it will take decades of work to learn what we need to know. It's true that adult stem cell research has provided some immediate results; this is due to the fact that adult stem cells are multipotent. That is, they are not as flexible as embryonic stem cells; it has proven easier to coax them to do what you want. Also, stem cells taken from your body create autologous materials; you won't need to take immune suppressant drugs for the rest of your life following a transplant. However, embryonic stem cell research has a great deal of value. One reason is that embryonic stem cells are pluripotent; they can become any cell in the body. The mere fact that they are different from adult stem cells makes them ideal objects of research. Also, embryonic stem cells are easier to culture; they can survive many more generations. This also makes them ideal for researchers with long research timelines. Both embryonic and adult stem cells are needed for research; there is a difference between making something and being able to learn something essential. A comparison of the two types of cells may provide essential clues. And, as I said at the start, we're just at the start of stem cell research. So, I reiterate what I said in my comment to the article, I hope that stem cell research will not be hindered."
(Bill Christensen 2/5/2008 4:30:50 PM)
|"To Bill's comment above: You are omitting an important point, possibly from ignorance: There has already been research that allows scinetists to click the biochemical 'switch' over and make the adult stem cells, for all intents and purposes, as biologically 'flexible' as the embryonic stem cells. So they are now (A) as experimentally viable as any embryonic research ever will be (B) allow, as you pointed out, the avoidance of autoimmune difficulties by using the patient's own cells, (C) have a proven track record of breakthroughs and applications ten times as long as the embryonic research (which has largely been a costly series of failures) and (D) does not have the moral and ethical baggage that the destruction of human embryos does.
Adult stem cell research is wonderful and beneficial and gets my wholehearted support.
Embryonic stem cell research shouldn't be supported with the same vigor or funding for BOTH moral and financial reasons when it is a technology that is both unnecessary and unproductive in additional to being morally objectionable to many.
( 2/5/2008 6:13:45 PM)
|"Are you referring to induced pluripotent stem cells (first produced from human cells in 2007)?
"Induced pluripotent stem cells, commonly abbreviated as iPS cells or iPSCs, are a type of pluripotent stem cell artificially derived from a non-pluripotent cell, typically an adult somatic cell, by inserting certain genes.
Induced Pluripotent Stem Cells are believed to be identical to natural pluripotent stem cells, such as embryonic stem cells in many respects, such as the expression of certain stem cell genes and proteins, chromatin methylation patterns, doubling time, embryoid body formation, teratoma formation, viable chimera formation, and potency and differentiability, but the full extent of their relation to natural pluripotent stem cells is still being assessed."
From Induced pluripotent stem cell.
There's that "still being assessed" problem... Anyway, it doesn't make any sense to me to try to create an artificial iPSC when you might as well work with the originals - embryonic stem cells.
Of course, there's always my aforementioned 'ignorance problem' - I don't have any formal training in biology. I appreciate the discussion."
(Bill Christensen 2/5/2008 7:13:48 PM)
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