Science Fiction
Dictionary
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
 |
Mice Get Smarter By Losing Cdk5 Enzyme
Just when you think you have a better mousetrap - they build a smarter mouse. Texas University research suggests that mice with the Cdk5 enzyme knocked out learn faster and detect changes in their environment more rapidly. The study results were published in the journal Nature Neuroscience this week.
"Everything is more meaningful to these mice," he said. "The increase in sensitivity to their surroundings seems to have made them smarter."
The key was removing the gene for Cdk5 only in the brain, and only after the mice had grown to adulthood. A technique called "conditional knock-out" was used, which results in a tissue-specific inactivation of a gene.
The reconfigured mice are better able to find their way through a water maze - and avoiding the electroshock parts. When crafty researchers altered the maze, the modified mice were the first to realize the change and learn the new structure.
This can be achieved by means of a recombinase, which is an enzyme that deletes the DNA fragment located between the two recombinase-specific sites. A mouse bearing the recombinase-specific sites is bred with a mouse expressing the recombinase. The tissue-specific expression of the recombinase allows the inactivation of the gene of interest only in the tissue where the recombinase is expressed
Like the rest of us, science fiction writers have diligently set up scenarios in which humans could become smarter. In Philip K. Dick's 1964 novel The Three Stigmata of Palmer Eldritch, people could actually get more brains if they wanted to be smarter. A procedure called E Therapy was performed to increase the size of their brains:
Amazingly, researchers have been able to grow larger brains in mice; see the second part of Philip K. Dick's Bubblehead Brainiacs for details. Researchers have also tried creating mouse-human hybrids to make them smarter (mice, that is); see Mouse With Human Brain May Live for details.
Via CBC News; see also conditional knock out mouse.
"It's pretty rare that you make mice 'smarter,' so there are a lot of cognitive implications," the study's senior author, Dr. James Bibb, said in a news release.
The man's head reminded Hnatt of a photograph he had once seen in a textbook; the photo had been labeled hydrocephalic. The same enlargement above the browline; it was clearly domelike and oddly fragile-looking and he saw at once why these well-to-do persons who had evolved were popularly called bubbleheads.
(Read more about bubbleheads)
Scroll down for more stories in the same category. (Story submitted 5/29/2007)
Follow this kind of news @Technovelgy.| Email | RSS | Blog It | Stumble | del.icio.us | Digg | Reddit |
Would
you like to contribute a story tip?
It's easy:
Get the URL of the story, and the related sf author, and add
it here.
Comment/Join discussion ( 2 )
Related News Stories - (" Biology ")
Lunar Biorepository Proposed For Cryo-Preservation Of Earth Species
'...there was no one alive who had ever seen them. But they existed in the Life Bank.' - John Varley, 1977.
Let's Make Slaver Sunflowers! Engineering Plants To Reflect Light
'The mirror-blossom was a terrible weapon.' - Larry Niven, 1965.
Machete-Wielding Philodendron Isn't Going To Take It Anymore
'The tree ended its wild larruping, stood like a dreaming giant liable to wake into frenzy at any moment.' - Eric Frank Russell, 1943.
Tsunami Forecasts Improved By Ionosphere Signals
'Swifter than any tide could ebb, the water was receding from the shore.'
Technovelgy (that's tech-novel-gee!) is devoted to the creative science inventions and ideas of sf authors. Look for the Invention Category that interests you, the Glossary, the Invention Timeline, or see what's New.
Science Fiction
Timeline
1600-1899
1900-1939
1940's 1950's
1960's 1970's
1980's 1990's
2000's 2010's
Current News
Mechazilla Arms Catch A Falling Starship, But Check Out SF Landing-ARMS
'...the rocket’s landing-arms automatically unfolded.'
A System To Defeat AI Face Recognition
'...points and patches of light... sliding all over their faces in a programmed manner that had been designed to foil facial recognition systems.'
Robot Hand Separate From Robot
'The crawling, exploring object was V-Stephen's surgeon-hand...'
Hybrid Wind Solar Devices
'...the combined Wind-Suncatcher, like a spray of tulips mounted fanwise.'
Is Optimus Autonomous Or Teleoperated?
'I went to the control room where the three other men were manipulating their mechanical men.'
Robot Masseuse Rubs People The Right Way
'The automatic massager began to fumble gently...'
Solar-Powered Space Trains On The Moon
'The low-slung monorail car, straddling its single track, bored through the shadows on a slowly rising course.'
Drone Deliveries Instead Of Waiters In Restaurants?
'It was a smooth ovoid floating a few inches from the floor...'
Optimus Robot Can Charge Itself
'... he thrust in his charging arm to replenish his store of energy.'
Skip Movewear Arc'teryx AI Pants
'...the terrible Jovian gravity that made each movement an effort.'
'Robovan' Name Already Taken - Elon, Try These
There are alternative names that are probably in the public domain by now.
How Old Are Tesla Designs?
You be the judge.
Is Your Autonomous Tractor Safe?
'The field-minder finished turning the top-soil of a two-thousand-acre field.'
Smart TVs Are Listening!
'You had to live -- did live, from habit that became instinct -- in the assumption that every sound you made was overheard...'
Police Drones In China Would Like To Have A Word With You
''OVERRIDE,' the City Fathers said suddenly, without being asked anything at all.'
Oh Great (Part 2), Fence-Climbing Robots
Please, no stingers.
