Bioengineered Mouse Tooth Bud Successfully Implanted

A tiny bioengineered tooth bud has been successfully created and implanted in an adult mouse by Tokyo University researchers. They took epithelial cells and mesenchymal cells (about 50,000 each) from a mouse embryo and cultivated them together in a collagen-based medium to create a tiny tooth bud.

Here, we report a successful fully functioning tooth replacement in an adult mouse achieved through the transplantation of bioengineered tooth germ into the alveolar bone in the lost tooth region. We propose this technology as a model for future organ replacement therapies. The bioengineered tooth, which was erupted and occluded, had the correct tooth structure, hardness of mineralized tissues for mastication, and response to noxious stimulations such as mechanical stress and pain in cooperation with other oral and maxillofacial tissues.


(Bioengineered mouse tooth bud)

I first read about this idea in William Gibson's 1984 novel Neuromancer:

When Angelo smiled, revealing the razor-sharp canines of some large animal, Case was actually relieved. Toothbud transplants. He'd seen that before.
(Read more about toothbud transplants)

From Fully functional bioengineered tooth replacement as an organ replacement therapy via Pink Tentacle.

Scroll down for more stories in the same category. (Story submitted 8/7/2009)

Follow this kind of news @Technovelgy.

| Email | RSS | Blog It | Stumble | del.icio.us | Digg | Reddit |

Would you like to contribute a story tip? It's easy:
Get the URL of the story, and the related sf author, and add it here.

Comment/Join discussion ( 3 )

Related News Stories - (" Biology ")

Oil from Algae - Can It Be Done?
'We dump everything that's waste into the tanks, pump the oil off the top.' - Hal Clement, 1950.

Amazing 'Hybrid' Solar-Powered Sea Slug Does Photosynthesis
Thank goodness for Star Trek.

Should You Submit Your DNA To A Database?
Consumer DNA services are often inaccurate.

Humans Evolve Deep Diving Abilities
Sounds like '60s sci-fi to me.

 

Google
  Web TechNovelgy.com   

Technovelgy (that's tech-novel-gee!) is devoted to the creative science inventions and ideas of sf authors. Look for the Invention Category that interests you, the Glossary, the Invention Timeline, or see what's New.

 

 

 

 

 

Current News

SWEEPER Robot Peter Piper Picking Peppers
'... little machines, that went from plant to plant, apparently on caterpillar tracks, cutting off the ripe fruit.'

Oil from Algae - Can It Be Done?
'We dump everything that's waste into the tanks, pump the oil off the top.'

Moving Whole Planets, Revisited
There was a lot of work done on this idea over the years.

Disney Keeps Backups Of Star Wars Franchise Actors
'She is a personality-construct, a congeries of software agents...'

Farming In Space Starts With Mycorrhiza
'The inner leaves were beginning to curl faster than the outer leaves.'

Jaguar I-Pace Audible Vehicle Alert System For EVs
'Of course not a vehicle moved by means of internal explosions of a derivative of rock oil...'

Autonomous 'Fiberbots' Weave Large Structures
'It extrudes material like a spider.'

Birds Aren't Real - Wake Up, California! (With Bird Watching Guide)
'When he had first built them, they had been crude indeed, flying mechanisms with little more than a reflex-response unit.'

Self-Healing Material Pulls Carbon Out Of The Air
'... could seal the punctures.'

IRL Glasses Block Screens, Limit Vision To Real Life
'If you couldn't see the ads, how would you know what was fashionable?'

Testing The Single-Person Spacecraft
'...the lower part of the suit was simply a rigid cylinder.'

Shapeshifting Materials Transform By Light
'Its lines wavered, flowed, and then painfully reformed.'

Fully Automated Farm Iron Ox Hydroponics
'Had these machines in some incredible fashion been provided with brains?'

BrainNet Social Network Of Brains
'I used my implant to tell MILLIE what we wanted and she took care of it'

Phil Nuyttnn's City Under The Sea
'Under the lower roof there was no water, but a clear and luminous atmosphere...'

IONITY Opens First 10 Fast-Charging Stations
'Recharge the batteries... in almost every town and village...'

More SF in the News Stories

More Beyond Technovelgy science news stories

Home | Glossary | Invention Timeline | Category | New | Contact Us | FAQ | Advertise |
Technovelgy.com - where science meets fiction™

Copyright© Technovelgy LLC; all rights reserved.