Science Fiction
Dictionary
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
 |
Micromasonry 'Biological Legos' Building New Organs
One of the problems with building your own organs from scratch is getting the 3-dimensional structure right. MIT-Harvard researchers are working on biological legos to grow a 3D organ.
The new technique, called micromasonry, involves tiny blobs of a gel-like material. Each tiny blob contains individual cells; the blobs stick together in a desired structure.
( half sphere of polymer cubes built by MIT-Harvard researchers )
A variety of techniques have been evolved for printing two-dimensional strips of organic matter (see Hungry? Print Yourself Some Bacon and Cultured Meat Straight From The Vat for two approaches).
"That works, but it often lacks a controlled microarchitecture," says Ali Khademhosseini, assistant professor at the MIT-Harvard Division of Health Sciences and Technology (HST), is also an assistant professor at Brigham and Women's Hospital. "You don't get tissues with the same complexity as normal tissues."
Gomez Fernandez and Khademhosseini have used their technique to build tiny tubes that could function as capillaries, which could provide an engineered organ with its blood supply.
The HST researchers built their "biological Legos" by encapsulating cells within a polymer called polyethylene glycol (PEG), which has many medical uses. Their version of the polymer is a liquid that becomes a gel when illuminated, so when the PEG-coated cells are exposed to light, the polymer hardens and encases the cells in cubes with side lengths ranging from 100 to 500 millionths of a meter.Once the cells are in cube form, they can be arranged in specific shapes using templates made of PDMS, a silicon-based polymer used in many medical devices. Both template and cell cubes are coated again with the PEG polymer, which acts as a glue that holds the cubes together as they pack themselves tightly onto the scaffold surface.
After the cubes are arranged properly, they are illuminated again, and the liquid holding the cubes together solidifies. When the template is removed, the cubes hold their new structure.
SF fans have waited a long time for artificially grown organs; Larry Niven wrote about the idea in his 1968 novel A Gift From Earth.
From Science Daily.
Scroll down for more stories in the same category. (Story submitted 5/16/2010)
Follow this kind of news @Technovelgy.| Email | RSS | Blog It | Stumble | del.icio.us | Digg | Reddit |
Would
you like to contribute a story tip?
It's easy:
Get the URL of the story, and the related sf author, and add
it here.
Comment/Join discussion ( 0 )
Related News Stories - (" Medical ")
MIT Computerized Bionic Leg Is Part Of The User
'The leg was to function, in a way, as a servo-mechanism operated by Larry’s brain, through the mediation of the electronic brain in the leg.' - Charles Recour, 1949.
Bone-Building Drug Evenity Approved
'Compounds devised by the biochemists for the rapid building of bone...' - Edmond Hamilton, 1932.
BrainBridge Concept Transplant Of Human Head Proposed
'Briquet’s head seemed to think that to find and attach a new body to her head was as easy as to fit and sew a new dress.' - Alexander Belaev (1925)
Natural Gait With Prosthetic Connected To Nervous System
'The leg was to function, in a way, as a servo-mechanism operated by Larry’s brain...' - Charles Recour, 1949.
Technovelgy (that's tech-novel-gee!) is devoted to the creative science inventions and ideas of sf authors. Look for the Invention Category that interests you, the Glossary, the Invention Timeline, or see what's New.
Science Fiction
Timeline
1600-1899
1900-1939
1940's 1950's
1960's 1970's
1980's 1990's
2000's 2010's
Current News
Amazing Photonic
'That sail will be twenty thousand miles at the wide part.'
Amazing Photonic Crystal Light Sail
'That sail will be twenty thousand miles at the wide part.'
Rogue AI Replicated Itself
'Sapiro’s computer just kept dialing at random, hanging up on humans, until it got a fellow computer of the same type as itself.'
HandelBot Helps Two-Handed Robots Learn Piano
'I request that you feed the correlation between those dots and the levers of the panel into my memory banks.'
Woven Fiber Electronic Skin For Robots
'... all the feel and appearance of human flesh and epidermis.'
When AI Takes Its First Breath
Any suggestions?
Chinese Aircar Light And Airy, Not For Blade Runners
Daytime version.
The Morphing Wheel And The Smartwheel
'If you surf over a bump, the spokes contract to roll over it.'
Transporting Antimatter
'...drawing plans for the magnetic tongs and bed plates and relays.'
Polish Turns Your Nail Into A Stylus
'He wrote on it, using the pointed fingernail of his right forefinger...'
I Wish This Plaudit Pin Was More Like A Wristpad
'Frank was cursing into his wristpad, switching between Arabic and English.'
World's Largest Teleoperated Arm
'...a pair so huge that Stevens could not conceive a use for it..'
Japan's AI Buddharoid Automonks
'...each of them is a neural mapping of the mind of a Tibetan monk who actually lived.'
MIT Computerized Bionic Leg Is Part Of The User
'The leg was to function, in a way, as a servo-mechanism operated by Larry’s brain, through the mediation of the electronic brain in the leg.'
The New Habitable Zones Include Asimov's Ribbon Worlds
'...there's a narrow belt where the climate is moderate.'
California Governor Candidate Calls For Voting By Phone
'... every veephone on the continent would display, over and over, two propositions.'
