Youthful Brain With A Flip Of A Molecular Switch
The flip of a single molecular switch helps create the mature neuronal connections that allow the brain to bridge the gap between adolescent impressionability and adult stability. Now Yale School of Medicine researchers have reversed the process, recreating a youthful brain that facilitated both learning and healing in the adult mouse.
By monitoring the synapses in living mice over weeks and months, Yale researchers have identified the key genetic switch for brain maturation a study released March 6 in the journal Neuron. The Nogo Receptor 1 gene is required to suppress high levels of plasticity in the adolescent brain and create the relatively quiescent levels of plasticity in adulthood. In mice without this gene, juvenile levels of brain plasticity persist throughout adulthood. When researchers blocked the function of this gene in old mice, they reset the old brain to adolescent levels of plasticity.
“These are the molecules the brain needs for the transition from adolescence to adulthood,” said Dr. Stephen Strittmatter. Vincent Coates Professor of Neurology, Professor of Neurobiology and senior author of the paper. “It suggests we can turn back the clock in the adult brain and recover from trauma the way kids recover.”
Readers of Analog recall the "Kitten" series by Jeffrey D. Kooistra; "Puff" [Analog, December 1993], "Fluffy" [Analog, June 1996], and "Snowball" [Analog, July 1996].
The plot: scientist invents cat that never ages beyond being a kitten. Never-ending kitten-itude leads to constant learning at a high rate leads to hyperintelligent kittens leads to murder.
Via Yale; thanks to Winchell Chung for the tip on the story.
Scroll down for more stories in the same category. (Story submitted 3/27/2013)
Follow this kind of news @Technovelgy.
| Email | RSS | Blog It | Stumble | del.icio.us | Digg | Reddit |
you like to contribute a story tip?
Get the URL of the story, and the related sf author, and add
Comment/Join discussion ( 1 )
Related News Stories -
Hackers Insert Malware Into DNA
'They tied the memory to the bloodline and that was their record!' -
Worms Eat Plastic Now
'Slowly and inexorably, the rate of dissolution increased...' - Davis/Pedlar, 1971.
Mini-Brains In A Dish
'Cultured brains on a slab.' - Peter Watts, 1999.
NASA's Prototype Lunar Greenhouse For Mars And Moon
'In contrast to the airless desolation outside, the interior of this five-acre greenhouse was the one most desirable place to be.' - Raymond Z. Gallun, 1951.
Technovelgy (that's tech-novel-gee!)
is devoted to the creative science inventions and ideas of sf authors. Look for
the Invention Category that interests
you, the Glossary, the Invention
Timeline, or see what's New.
Tesla Semi 'Electrotruck' Unveiled
Elon Musk unveils yet another technological marvel.
Watch What People Are Seeing Via Brain Scanning
'had managed to see through the other man's eyes as the other man, all unaware, washed their Zis limousine sixteen hundred meters away...'
Integrated Circuits Printed Right Onto Fabric!
'...a shirt that displayed email on its sleeve.
Interstellar Asteroid Visits Our Solar System
'This asteroid had whirled in from the cold of the interplanetary space...'
PRIMA Bionic Vision Restoration
'The VISOR... was a medical device used in the Federation to aid patients who have suffered loss of eyesight...'
Audi Traffic Jam Pilot Knows If You're Sleeping
'Even here, riding a garbage truck to eternity, the machine watched him...'
UM Hall Thruster Breaks Records
Someday, we'll see an ion drive used to get to Mars.
Ionity Ultra-fast Charging Station Network
'Recharge the batteries... in almost every town and village...'
VAuth Voice Security Wearable From University of Michigan
'Siri, I gave you a voice command...' 'Yes, but do I know you?'
Ubiquiti FrontRow Camera Records Your Life
Why be choosy? Just upload your whole life to the Internet, and be done with it.
Ancient Ocean On Ceres?
'We sailed gently forward, hull down to the asteroid's surface... A little sea was now beneath us.'
SmileCloud Bubloons Are Custom Clouds
'Spurgle kicked at the letter G... It was a monstrous white thing, ten feet thick, half a city block long...'
Cassie 'Halfbot' Best Half (Lower) Of Humanoid Robot
We can always make it limp along if it gets threatening.
Autonomous Concrete Floor Finishing Robot
Keep those construction site robots coming.
Musk Tweets A Boring Tunnel Pic
'We hit the sub-basement and went at once to the express tubes...'
Shelley.ai AI Terrifies Thanks To Reddit's Nosleep
'How can you compete with IBM?'
More SF in the News Stories
More Beyond Technovelgy science news stories