Youthful Brain With A Flip Of A Molecular Switch
The flip of a single molecular switch helps create the mature neuronal connections that allow the brain to bridge the gap between adolescent impressionability and adult stability. Now Yale School of Medicine researchers have reversed the process, recreating a youthful brain that facilitated both learning and healing in the adult mouse.
By monitoring the synapses in living mice over weeks and months, Yale researchers have identified the key genetic switch for brain maturation a study released March 6 in the journal Neuron. The Nogo Receptor 1 gene is required to suppress high levels of plasticity in the adolescent brain and create the relatively quiescent levels of plasticity in adulthood. In mice without this gene, juvenile levels of brain plasticity persist throughout adulthood. When researchers blocked the function of this gene in old mice, they reset the old brain to adolescent levels of plasticity.
“These are the molecules the brain needs for the transition from adolescence to adulthood,” said Dr. Stephen Strittmatter. Vincent Coates Professor of Neurology, Professor of Neurobiology and senior author of the paper. “It suggests we can turn back the clock in the adult brain and recover from trauma the way kids recover.”
Readers of Analog recall the "Kitten" series by Jeffrey D. Kooistra; "Puff" [Analog, December 1993], "Fluffy" [Analog, June 1996], and "Snowball" [Analog, July 1996].
The plot: scientist invents cat that never ages beyond being a kitten. Never-ending kitten-itude leads to constant learning at a high rate leads to hyperintelligent kittens leads to murder.
Via Yale; thanks to Winchell Chung for the tip on the story.
Scroll down for more stories in the same category. (Story submitted 3/27/2013)
Follow this kind of news @Technovelgy.
| Email | RSS | Blog It | Stumble | del.icio.us | Digg | Reddit |
you like to contribute a story tip?
Get the URL of the story, and the related sf author, and add
Comment/Join discussion ( 1 )
Related News Stories -
Amazing 'Hybrid' Solar-Powered Sea Slug Does Photosynthesis
Thank goodness for Star Trek.
Should You Submit Your DNA To A Database?
Consumer DNA services are often inaccurate.
Humans Evolve Deep Diving Abilities
Sounds like '60s sci-fi to me.
Researchers Create Bowls, Coils, Ripples Of Living Tissue
'... biological robots were not living creatures.' - Arthur C. Clarke, 1972.
Technovelgy (that's tech-novel-gee!)
is devoted to the creative science inventions and ideas of sf authors. Look for
the Invention Category that interests
you, the Glossary, the Invention
Timeline, or see what's New.
Sleeep PRO Earplug For Maximum Rest
'Merton... placed the electrodes of the sleep-inducer on his forehead.'
Inspired By Japan, Nap Pods For Hajj
It's always a good time for a nap.
Amphibio 3D Printed Gill Shirt
'... we can descend and live down there at one of those year-round aquatic resorts.'
How Do You Put An Asteroid Into Earth Orbit? Carefully!
'...she would have to be coaxed by another series of pats into a circular orbit.'
PD Aerospace Space Plane By 2023
'The sleek, tapered space shuttle lay immobile upon the private landing field...'
Foldimate Folds Your Clothes Perfectly
Look ma, my room is clean! I can hear you now.
Robots Help People Get Dressed, As Predicted In 1931
Yes, people of the future, robots will dress you.
International Space Station Leak Plugged - With Finger
'These tag-alongs search out stray leaks.'
Robot Snake Flies, Fights Fires
Just a prototype, but still amazing.
IPAL Chinese Robot Babysitter
'But Nanny is different...'
ZKZM-500 LASER Assault Rifle
'The Iranian reached back into the locker and got a pair of laserifles.'
LA Subway Scanner, As Seen In 'Total Recall'
'I'm afraid to tell you this Mr. Quaid, but you have suffered a schizoed embolism...'
Sion Electric Car Covered With Solar Panels
'It drew its power from six square yards of sunpower screens on its low curved roof.'
PAL-V Liberty Flying Helicopter Car
'...lifted themselves to skimming flight upon whirling helicopters."
Space Drones - UK's Effective Space To Launch Rocket Tugs
'Twenty rocket tugs towed it from its Earth hangar out into space.'
DIY Autonomous Robot Detects Trash
'The search-bug detached itself and rolled forward.'
More SF in the News Stories
More Beyond Technovelgy science news stories