Convert your iPhone to a handheld biosensor with this cradle and app developed by University of Illinois at Urbana-Champaign researchers.
(iPhone-based handheld biosensor)
Utilizing its integrated camera as a spectrometer, we demonstrate the use of a smartphone as the detection instrument for a label-free photonic crystal biosensor. A custom-designed cradle holds the smartphone in fixed alignment with optical components, allowing for accurate and repeatable measurements of shifts in the resonant wavelength of the sensor. Externally provided broadband light incident upon an entrance pinhole is subsequently collimated and linearly polarized before passing through the biosensor, which resonantly reflects only a narrow band of wavelengths. A diffraction grating spreads the remaining wavelengths over the camera's pixels to display a high resolution transmission spectrum.
The photonic crystal biosensor is fabricated on a plastic substrate and attached to a standard glass microscope slide that can easily be removed and replaced within the optical path.
A custom software app was developed to convert the camera images into the photonic crystal transmission spectrum in the visible wavelength range, including curve-fitting analysis that computes the photonic crystal resonant wavelength with 0.009 nm accuracy.
We demonstrate the functionality of the system through detection of an immobilized protein monolayer, and selective detection of concentration-dependent antibody binding to a functionalized photonic crystal.
We envision the capability for an inexpensive, handheld biosensor instrument with web connectivity to enable point-of-care sensing in environments that have not been practical previously.
Science fiction fans have been teased with the idea of a powerful handheld biosensor for quite a while. In the 1960's, fans of Star Trek (TOS) recall the handheld tricorders used by both Mr. Spock and Dr. McCoy.
More specifically, though, I recall the boink biosensor from Richard Preston's 1997 novel The Cobra Event and the WAGD germ detector from Greg Bear's excellent 2007 novel Quantico.
Drug To Regenerate Teeth In Humans
'We want to do something to help those who are suffering from tooth loss or absence,' said lead researcher Katsu Takahashi.
Technovelgy (that's tech-novel-gee!)
is devoted to the creative science inventions and ideas of sf authors. Look for
the Invention Category that interests
you, the Glossary, the Invention
Timeline, or see what's New.
Humanoid Robots Building Humanoid Robots
''Pardon me, Struthers,' he broke in suddenly... 'haven't you a section of the factory where only robot labor is employed?''
Stratospheric Solar Geoengineering From Harvard
'Pina2bo would have to operate full blast for many years to put as much SO2 into the stratosphere as its namesake had done in a few minutes.'