Science Fiction Dictionary
A  B  C  D  E  F  G  H  I  J  K  L  M  N  O  P  Q  R  S  T  U  V  W  X  Y  Z

 

Human On A Chip

Army Scientists at the Edgewood Chemical Biological Center and academia collaborators have been conducting research of "organs" on microchips. ECBC will test the human-on-a-chip against chemical warfare agent to learn more about how the body will respond to agent exposure and explore various treatment options for exposures.


(Human-on-a-chip technology)

ECBC scientists were already undergoing research on four organs -- the heart, liver, lung and the nervous system -- when DTRA solicited a call for proposals. Then once the proposal was awarded, the center began working specifically on the heart, liver, lung and the circulatory system. Dr. Harry Salem, ECBC's chief scientist for Life Sciences, leads ECBC's in vitro research team working with stem cells.

"Stem cells are a relatively new field of research," Salem said. "The stem cells that ECBC uses … are made from adult skin cells called induced pluripotent stem cells."

Each organ-on-a-chip is about the size of a thumb drive and is an organoid, or a small swatch of human tissue, designed to mimic the properties of an actual human organ. They are made up of multiple layers of cells growing on a membrane and are connected to each other by microfluidics, tiny micro channels that copy the function of blood vessels. Their primary purpose is to take the place of animal research.

It is anticipated that new predictive models of toxicity will result from the more accurate human-on-a-chip testing. This will save both time and money. Pharmaceuticals tested on animals fail to work on humans 90 percent of the time. This technology will result in fewer test failures. Scientists will be able to narrow their research efforts by identifying which therapeutics will be effective or fail early on in the testing process.

"The human-on-a-chip promises to accelerate the pace of research and consequently scientific breakthroughs," Dr. Russell Dorsey, a research microbiologist and one of the members performing the in vitro testing at ECBC, said. "For the military, our human-on-a-chip research will save actual warfighters' lives."

I don't know any earlier references to the idea that living cells can be a part of electronic devices than those of Philip K. Dick. Consider the swibble from his 1955 story Service Call or the Ampek F-a2 Recording System from his 1966 novel The Simulacra:

Nat Flieger reflexively poured water into a cup and fed the living protoplasm incorporated into the Ampek F-a2 recording system which he kept in his office; the Ganymedean life form did not experience pain and had not yet objected to being made over into a portion of an electronic system... neurologically it was primitive, but as an auditory receptor it was unexcelled...
(Read more about the Ampek F-a2 Recording System)

Via US Army.

Scroll down for more stories in the same category. (Story submitted 9/30/2013)

Follow this kind of news @Technovelgy.

| Email | RSS | Blog It | Stumble | del.icio.us | Digg | Reddit |

Would you like to contribute a story tip? It's easy:
Get the URL of the story, and the related sf author, and add it here.

Comment/Join discussion ( 1 )

Related News Stories - (" Medical ")

MouthPad Supports Head And Tongue Tracking
'The operation that had transformed half his body... had located the control switchboard in his teeth.'- Alfred Bester, 1956.

Drug Induces Hibernation-Like State In Humans
'... drugged and chilled and stowed in sleep tanks.' - Robert Heinlein, 1951.

Drug To Regenerate Teeth In Humans
'We want to do something to help those who are suffering from tooth loss or absence,' said lead researcher Katsu Takahashi.

Illustrating Classic Heinlein With AI
'Stasis, cold sleep, hibernation, hypothermia, reduced metabolism, call it what you will - the logistics-medicine research teams had found a way to stack people like cordwood and use them when needed.' - Robert Heinlein, 1956

 

Google
  Web TechNovelgy.com   

Technovelgy (that's tech-novel-gee!) is devoted to the creative science inventions and ideas of sf authors. Look for the Invention Category that interests you, the Glossary, the Invention Timeline, or see what's New.

 

 

 

 

Science Fiction Timeline
1600-1899
1900-1939
1940's   1950's
1960's   1970's
1980's   1990's
2000's   2010's

Current News

AI Welfare Position At Anthropic Filled By Human
'You’re the robopsychologist of the plant, so you’re to study the robot itself...'

Marslink Proposed By SpaceX
'It was the heart of the Solar System's communication line...'

Simple Way To Defeat AI Face Recognition
'... designed to foil facial recognition systems.'

Wood-Panelled LignoSat Launched
'The Consul remembered his first glimpse of the kilometer-long treeship...'

Laser-Beam Welding In Orbital Factories
'His contract with Space Industries required him to work summers in their orbital factory.'

'Iceberg House' Of Travis Kelce Reflects Science Fiction Of Past Century
'The basement was huge... carved deep into the rock that folded up to underlie the ridge...'

Mechazilla Arms Catch A Falling Starship, But Check Out SF Landing-ARMS
'...the rocket’s landing-arms automatically unfolded.'

A System To Defeat AI Face Recognition
'...points and patches of light... sliding all over their faces in a programmed manner that had been designed to foil facial recognition systems.'

Robot Hand Separate From Robot
'The crawling, exploring object was V-Stephen's surgeon-hand...'

Hybrid Wind Solar Devices
'...the combined Wind-Suncatcher, like a spray of tulips mounted fanwise.'

Is Optimus Autonomous Or Teleoperated?
'I went to the control room where the three other men were manipulating their mechanical men.'

Robot Masseuse Rubs People The Right Way
'The automatic massager began to fumble gently...'

Solar-Powered Space Trains On The Moon
'The low-slung monorail car, straddling its single track, bored through the shadows on a slowly rising course.'

Drone Deliveries Instead Of Waiters In Restaurants?
'It was a smooth ovoid floating a few inches from the floor...'

Optimus Robot Can Charge Itself
'... he thrust in his charging arm to replenish his store of energy.'

Skip Movewear Arc'teryx AI Pants
'...the terrible Jovian gravity that made each movement an effort.'

More SF in the News Stories

More Beyond Technovelgy science news stories

Home | Glossary | Invention Timeline | Category | New | Contact Us | FAQ | Advertise |
Technovelgy.com - where science meets fiction™

Copyright© Technovelgy LLC; all rights reserved.