Gene-Edited Muscle Dogs From China

Gene editing has been used for the first time to produce customized dogs; Chinese researchers have created beagles with double the muscle mass by deleting a gene called myostatin.


(China's gene-edited muscle dogs)

The dogs have “more muscles and are expected to have stronger running ability, which is good for hunting, police (military) applications,” Liangxue Lai, a researcher with the Key Laboratory of Regenerative Biology at the Guangzhou Institutes of Biomedicine and Health, said in an e-mail.

Lai and 28 colleagues reported their results last week in the Journal of Molecular Cell Biology, saying they intend to create dogs with other DNA mutations, including ones that mimic human diseases such as Parkinson’s and muscular dystrophy, in order to test drugs and other treatments. “The goal of the research is to explore an approach to the generation of new disease dog models for biomedical research,” says Lai. “Dogs are very close to humans in terms of metabolic, physiological, and anatomical characteristics.”

The Chinese beagle project was led by Lai and Gao Xiang, a specialist in genetic engineering of mice at Nanjing University. The dogs are being kept at the Guangzhou General Pharmaceutical Research Institute, which says on its website that it breeds more than 2,000 beagles a year for research. Beagles are commonly used in biomedical research in both China and the U.S.

Genome editing refers to newly developed techniques that let scientists easily disable genes or rearrange their DNA letters.

SF fans may recall the modded dogs in John Brunner's 1976 novel Shockwave Rider; they were genetically modified for higher intelligence, and were used to sniff out people who lie or use undesirable substances based on their body odor.

...something moved, emerging from shadow beside the workbench. A dog. A vast, slow-moving graceful dog whose ancestry might have included Great Dane, Irish wolfhound, possibly Husky or Chinook... plus something else, something strange, for its skull was improbably high-domed and its eyes, deep-set, were disturbingly uncanine.

"No need to be alarmed," the man rumbled... "Never met a dog like this before? You're in for an educational experience.

From Technology Review.

Scroll down for more stories in the same category. (Story submitted 10/15/2015)

Follow this kind of news @Technovelgy.

| Email | RSS | Blog It | Stumble | del.icio.us | Digg | Reddit |

Would you like to contribute a story tip? It's easy:
Get the URL of the story, and the related sf author, and add it here.

Comment/Join discussion ( 0 )

Related News Stories - (" Biology ")

Mushroom Eats Plastic, Saves Planet
Fungus Amongus, SaveUs!

Is There Extraterrestrial Life Here In The Solar System
'How fast is it moving? ...one meter per minute.' - Arthur C. Clarke, 1982.

Chinese Fern Helps Remediate Arsenic Soil
'Bioengeering had put out a spec report on the long crawly things five months back.' - Gregory Benford, 1983.

New Lifelike Material Powered By Artificial Metabolism
'... The biological robots were not living creatures.' - Arthur C. Clarke, 1972.

 

Google
  Web TechNovelgy.com   

Technovelgy (that's tech-novel-gee!) is devoted to the creative science inventions and ideas of sf authors. Look for the Invention Category that interests you, the Glossary, the Invention Timeline, or see what's New.

 

 

 

 

 

Current News

Nobe 3-Wheel Electric Vehicle Parking Like I, Robot
Spidercar, Spidercar, does whatever a spidercar does.

Michelin Self-Sealing Tires On Ford's Explorer
'...a seal of compressed plastifoam to save the air.'

Mushroom Eats Plastic, Saves Planet
Fungus Amongus, SaveUs!

Juggalo Face Paint Disrupts Facial Recognition
'... designed to foil facial recognition systems.'

Mojipic Smart Voice Vehicle Emojis
KITT, what's your response?

Unusual Twist On Woman Dates Robot
'My hearing, vision and awareness went along with that excellent imitation of a young Adonis...'

BrainNet Triple Telepathic Gaming Threat
'In the gloomy half-darkness the three idiots sat babbling.'

AVAS Noisemakers Required For EVs By EU
'...a sound tape to supply the noise of a soi-disant "[internal combustion]" engine...'

Pun Generation Via Neural Nets
'You said you wanted him to be able to distinguish between laugh-power in different gags...'

Blood Battery Robotic Fish
'With one fluid motion, it surged forward, plunged, and was gone.'

Lightyear One Solar-Powered Electric Car (Design By Heinlein)
'It drew its power from six square yards of sunpower screens on its low curved roof.'

'Agression Detectors' Don't Work When Spying On Students
'The professional agitators had also learned how to modulate their voices below the danger level...'

Mining Of Golden Asteroid Foretold In 1898 Science Fiction
'This must be a golden planet—this little asteroid.'

Miners! NASA Wants To License RASSOR Excavator
'The borers had been dismantled and packed away.'

Bee+ Robobee Now With Four Wings
'It was a tiny thing, scarcely more than an inch and a half in length...'

CNSILK Robotic Spider Builder
'We could certainly spin a web right through the Solar System, if we can think of a good use for one.'

More SF in the News Stories

More Beyond Technovelgy science news stories

Home | Glossary | Invention Timeline | Category | New | Contact Us | FAQ | Advertise |
Technovelgy.com - where science meets fiction™

Copyright© Technovelgy LLC; all rights reserved.