Gene-Edited Muscle Dogs From China

Gene editing has been used for the first time to produce customized dogs; Chinese researchers have created beagles with double the muscle mass by deleting a gene called myostatin.


(China's gene-edited muscle dogs)

The dogs have “more muscles and are expected to have stronger running ability, which is good for hunting, police (military) applications,” Liangxue Lai, a researcher with the Key Laboratory of Regenerative Biology at the Guangzhou Institutes of Biomedicine and Health, said in an e-mail.

Lai and 28 colleagues reported their results last week in the Journal of Molecular Cell Biology, saying they intend to create dogs with other DNA mutations, including ones that mimic human diseases such as Parkinson’s and muscular dystrophy, in order to test drugs and other treatments. “The goal of the research is to explore an approach to the generation of new disease dog models for biomedical research,” says Lai. “Dogs are very close to humans in terms of metabolic, physiological, and anatomical characteristics.”

The Chinese beagle project was led by Lai and Gao Xiang, a specialist in genetic engineering of mice at Nanjing University. The dogs are being kept at the Guangzhou General Pharmaceutical Research Institute, which says on its website that it breeds more than 2,000 beagles a year for research. Beagles are commonly used in biomedical research in both China and the U.S.

Genome editing refers to newly developed techniques that let scientists easily disable genes or rearrange their DNA letters.

SF fans may recall the modded dogs in John Brunner's 1976 novel Shockwave Rider; they were genetically modified for higher intelligence, and were used to sniff out people who lie or use undesirable substances based on their body odor.

...something moved, emerging from shadow beside the workbench. A dog. A vast, slow-moving graceful dog whose ancestry might have included Great Dane, Irish wolfhound, possibly Husky or Chinook... plus something else, something strange, for its skull was improbably high-domed and its eyes, deep-set, were disturbingly uncanine.

"No need to be alarmed," the man rumbled... "Never met a dog like this before? You're in for an educational experience.

From Technology Review.

Scroll down for more stories in the same category. (Story submitted 10/15/2015)

Follow this kind of news @Technovelgy.

| Email | RSS | Blog It | Stumble | del.icio.us | Digg | Reddit |

Would you like to contribute a story tip? It's easy:
Get the URL of the story, and the related sf author, and add it here.

Comment/Join discussion ( 0 )

Related News Stories - (" Biology ")

Amazing 'Hybrid' Solar-Powered Sea Slug Does Photosynthesis
Thank goodness for Star Trek.

Should You Submit Your DNA To A Database?
Consumer DNA services are often inaccurate.

Humans Evolve Deep Diving Abilities
Sounds like '60s sci-fi to me.

Researchers Create Bowls, Coils, Ripples Of Living Tissue
'... biological robots were not living creatures.' - Arthur C. Clarke, 1972.

 

Google
  Web TechNovelgy.com   

Technovelgy (that's tech-novel-gee!) is devoted to the creative science inventions and ideas of sf authors. Look for the Invention Category that interests you, the Glossary, the Invention Timeline, or see what's New.

 

 

 

 

 

Current News

LA Subway Scanner, As Seen In 'Total Recall'
'I'm afraid to tell you this Mr. Quaid, but you have suffered a schizoed embolism...'

Sion Electric Car Covered With Solar Panels
'It drew its power from six square yards of sunpower screens on its low curved roof.'

PAL-V Liberty Flying Helicopter Car
'...lifted themselves to skimming flight upon whirling helicopters."

Space Drones - UK's Effective Space To Launch Rocket Tugs
'Twenty rocket tugs towed it from its Earth hangar out into space.'

DIY Autonomous Robot Detects Trash
'The search-bug detached itself and rolled forward.'

Ancient Russian Walking Excavator Would Be Perfect RV
I don't need it to go fast, it just needs to amble along.

ELROI Satellite 'License Plate'
Robert Heinlein was thinking about this in 1941.

When Robots Beg For Their Lives
"Just what do you think you're doing... Dave.'

Do You Still Want A Folding Screen Phone?
'A paper thin polycarbon screen unfurled...'

'Snapchat Dysmorphia' Now A Thing, Say Plastic Surgeons
'The program raced up the screen one scan line at a time, subtly smoothing, deleting and coloring.'

Quiet Electric Cars Law Finalized By US Transportation Department
'... a sound tape to supply the noise'

Drone Assassin Fails To Kill Venezuelan President
'The spotter descends, and we think it searches the vicinity, looking for the victim's face...'

Stick-On Tape Speakers, As Predicted By Bruce Sterling
Flexible tape speakers, someday.

Bezos Invites You To New Life In Off-World Colonies
'A new life awaits you!'

Amazon's Rekognition System Sees Criminals In Congress
'... the imprint of her image on the telephoto cell.'

Build Your Own Space Suit For Cheap
'I'm going to pump the air from this room... so that the interior will be like airless and pressure-less space.'

More SF in the News Stories

More Beyond Technovelgy science news stories

Home | Glossary | Invention Timeline | Category | New | Contact Us | FAQ | Advertise |
Technovelgy.com - where science meets fiction™

Copyright© Technovelgy LLC; all rights reserved.