Hybrid Chips: Solid-State Device With Integrated Biological Cells

Columbia Engineering researchers have combined biological and solid-state components for the first time, opening the door to creating entirely new artificial biosystems.


(A biocell attached to a CMOS integrated circuit)
Illustration depicting a biocell attached to a CMOS integrated circuit
with a membrane containing sodium-potassium pumps in pores.
Energy is stored chemically in ATP molecules. When the energy is
released as charged ions (which are then converted to electrons to
power the chip at the bottom of the experimental device), the ATP
is converted to ADP + inorganic phosphate.
(credit: Trevor Finney and Jared Roseman/Columbia Engineering)

To build a prototype of their hybrid system, Shepard’s team packaged a CMOS integrated circuit (IC) with an ATP-harvesting “biocell.” In the presence of ATP, the system pumped ions across the membrane, producing an electrical potential (voltage)* that was harvested by the integrated circuit.

“We made a macroscale version of this system, at the scale of several millimeters, to see if it worked,” Shepard notes. “Our results provide new insight into a generalized circuit model, enabling us to determine the conditions to maximize the efficiency of harnessing chemical energy through the action of these ion pumps. We will now be looking at how to scale the system down.”

While other groups have harvested energy from living systems, Shepard and his team are exploring how to do this at the molecular level, isolating just the desired function and interfacing this with electronics. “We don’t need the whole cell,” he explains. “We just grab the component of the cell that’s doing what we want. For this project, we isolated the ATPases because they were the proteins that allowed us to extract energy from ATP.”

Science fiction fans no doubt are thinking about Philip K. Dick, who was fascinated by the idea of combing living cells and electronics. Consider the amazing swibble from his 1955 short story Service Call:

Patiently, the repairman explained elementary physics. "Swibble-culture is an organic phenotype evolved in a protein medium under controlled conditions. The directing neurological tissue that forms the basis of the swibble is alive, certainly, in the sense that it grows, thinks, feeds, excretes waste. Yes, it's definitely alive. But the swibble, as a functioning whole, is a manufactured item. The organic tissue is inserted in the master tank and then sealed.
(Read more about Dick's swibble)

I'd also include the Ampek F-a2 Recording System from his 1966 novel The Simulacra:

Nat Flieger reflexively poured water into a cup and fed the living protoplasm incorporated into the Ampek F-a2 recording system which he kept in his office; the Ganymedean life form did not experience pain and had not yet objected to being made over into a portion of an electronic system... neurologically it was primitive, but as an auditory receptor it was unexcelled.
(Read more about PKD's Ampek F-a2 Recording System )

Via KurzweilAI.

Scroll down for more stories in the same category. (Story submitted 11/30/2015)

Follow this kind of news @Technovelgy.

| Email | RSS | Blog It | Stumble | del.icio.us | Digg | Reddit |

Would you like to contribute a story tip? It's easy:
Get the URL of the story, and the related sf author, and add it here.

Comment/Join discussion ( 0 )

Related News Stories - (" Engineering ")

Prufrock The Newest Boring Machine
'It sounds to me as though you had invented a kind of metal earthworm...'

Stratuscent Electronic Nose
'It's picking up diphenyl compounds and tetra hydrocarbons.' - Michael Crichton, 1985.

Smart Contact Lenses Charges With 3D Printed Antenna
'He realized that it was not quite a clear lens.' - Vernor Vinge, 2001.

Physicist Inspired By SciFi And Seeing Back In Time
'Here is the chronoscope... Scansion depends upon a special curved field...'

 

Google
  Web TechNovelgy.com   

Technovelgy (that's tech-novel-gee!) is devoted to the creative science inventions and ideas of sf authors. Look for the Invention Category that interests you, the Glossary, the Invention Timeline, or see what's New.

 

 

 

 

 

Current News

Trash Sorting AI Robot Presages Skynet, Thanks A Lot
Keep your head down, Kyle Reese.

Electric Unicycle Is A Tumblebug
'A tumblebug does not give a man dignity, since it is about the size and shape of a kitchen stool, gyro-stabilized on a single wheel.'

Another Soil Bacterium Eats Plastic
'...the plastic was dissolved before his eyes.'

reLive Memorial Come Back As A Tree
'It was time - time to go again. She touched the leaf. She was wanted.'

Engineered Living Building Materials
'... it was the cheapest building material known.'

Draw Circuits With Conductive Ink
'It's rewiring things... squeezing silver toothpaste in a ribbon along the printed circuitry.'

Arkangel: Automatic Visual Censoring
It's whatever the Party says it is, Winston.

NASA Competition To Design A Bucket Drum For Moon Mining
'There was a heap of discarded ore where Grantline had carted and dumped it...'

Medical Assistant Robot May Roam The Halls Of Hospitals
'Take care, sir.'

No Autonomous Trucks? Wait, What?
'...it resembled conventional human-operated transportation vehicles, but with one exception -- there was no driver's cabin.'

As Big As A Biltong - World's Largest 3D Printer
'Huge and old, it squatted in the center of the settlement park... On the concrete platform... lay a heap of originals to be duplicated.'

Drones Used To Smuggle Contraband Into Prison
'And some mega chip inside so it never runs into anything and no cop ever sees it.'

Are You Ready For Commercial Space Travel?
'It wasn't a pleasant trip; it was a miserable trip on a miserable, undersized tourist rocket...'

Amplified Nerves Lead To Mind-Controlled Prosthetic Hands
'The electrical impulses generated by your brain command everything...'

FlyCroTug Micro Drones Do Heavy Lifting
'It extended three of its tiny arms sideways to lock on...'

Virtual Whitney Houston In Concert
Badda-Bing, Badda-Bang

More SF in the News Stories

More Beyond Technovelgy science news stories

Home | Glossary | Invention Timeline | Category | New | Contact Us | FAQ | Advertise |
Technovelgy.com - where science meets fiction™

Copyright© Technovelgy LLC; all rights reserved.