Hybrid Chips: Solid-State Device With Integrated Biological Cells

Columbia Engineering researchers have combined biological and solid-state components for the first time, opening the door to creating entirely new artificial biosystems.


(A biocell attached to a CMOS integrated circuit)
Illustration depicting a biocell attached to a CMOS integrated circuit
with a membrane containing sodium-potassium pumps in pores.
Energy is stored chemically in ATP molecules. When the energy is
released as charged ions (which are then converted to electrons to
power the chip at the bottom of the experimental device), the ATP
is converted to ADP + inorganic phosphate.
(credit: Trevor Finney and Jared Roseman/Columbia Engineering)

To build a prototype of their hybrid system, Shepard’s team packaged a CMOS integrated circuit (IC) with an ATP-harvesting “biocell.” In the presence of ATP, the system pumped ions across the membrane, producing an electrical potential (voltage)* that was harvested by the integrated circuit.

“We made a macroscale version of this system, at the scale of several millimeters, to see if it worked,” Shepard notes. “Our results provide new insight into a generalized circuit model, enabling us to determine the conditions to maximize the efficiency of harnessing chemical energy through the action of these ion pumps. We will now be looking at how to scale the system down.”

While other groups have harvested energy from living systems, Shepard and his team are exploring how to do this at the molecular level, isolating just the desired function and interfacing this with electronics. “We don’t need the whole cell,” he explains. “We just grab the component of the cell that’s doing what we want. For this project, we isolated the ATPases because they were the proteins that allowed us to extract energy from ATP.”

Science fiction fans no doubt are thinking about Philip K. Dick, who was fascinated by the idea of combing living cells and electronics. Consider the amazing swibble from his 1955 short story Service Call:

Patiently, the repairman explained elementary physics. "Swibble-culture is an organic phenotype evolved in a protein medium under controlled conditions. The directing neurological tissue that forms the basis of the swibble is alive, certainly, in the sense that it grows, thinks, feeds, excretes waste. Yes, it's definitely alive. But the swibble, as a functioning whole, is a manufactured item. The organic tissue is inserted in the master tank and then sealed.
(Read more about Dick's swibble)

I'd also include the Ampek F-a2 Recording System from his 1966 novel The Simulacra:

Nat Flieger reflexively poured water into a cup and fed the living protoplasm incorporated into the Ampek F-a2 recording system which he kept in his office; the Ganymedean life form did not experience pain and had not yet objected to being made over into a portion of an electronic system... neurologically it was primitive, but as an auditory receptor it was unexcelled.
(Read more about PKD's Ampek F-a2 Recording System )

Via KurzweilAI.

Scroll down for more stories in the same category. (Story submitted 11/30/2015)

Follow this kind of news @Technovelgy.

| Email | RSS | Blog It | Stumble | del.icio.us | Digg | Reddit |

Would you like to contribute a story tip? It's easy:
Get the URL of the story, and the related sf author, and add it here.

Comment/Join discussion ( 0 )

Related News Stories - (" Engineering ")

Road Noise Charges Electric Cars With Peugeot Piezoelectric Billboard
''... major cities of Earth have free electrical power conveniently processed from their own noise.' - Lloyd Biggle, Jr. 1956.

California Gets Shockwave Rider-Style Avoidance Zones
'It was cheaper to pay the refugees to go without up-to-the-minute equipment.'

Helios Modular Touch Screen Wall Lights
'The walls and ceiling bore an irregular spacing of illuminum tiles...' - Richard Morgan, 2003.

Harvest Water From Air With Sunlight
'The atmosphere yielded its moisture with reluctance.' - George Lucas, 1976.

 

Google
  Web TechNovelgy.com   

Technovelgy (that's tech-novel-gee!) is devoted to the creative science inventions and ideas of sf authors. Look for the Invention Category that interests you, the Glossary, the Invention Timeline, or see what's New.

 

 

 

 

 

Current News

Road Noise Charges Electric Cars With Peugeot Piezoelectric Billboard
''... major cities of Earth have free electrical power conveniently processed from their own noise.'

Unsinkable Metal Latest Gates Obsession
'A metal... light as cork.'

M-Blocks 2.0 Self-Assembling Robots
'Faster the cubes moved...'

NASA 'Broomstick' Recalls SciFi Ideas
'The appearance was enough like a giant witch's broom to justify the nickname.'

Orbital Display's Low Earth Orbit Advertisements
'A vast circle of scarlet stars came up into the greenish desert dusk.'

Neuromorphic Computing Hardare
'He had constructed an organ, a brain, of metal, entirely inorganic and lifeless...'

Vascularized Human Skin 3D Printed
Hey Fishboy!

Trillionaires Still Earth-Bound
'I shall never forget the sight... when the yellow gleam of the precious metal appeared under the star dust.'

Digit V2 Bipedal Robot From Agility Robotics
Oh, and now I suppose someone will develop the robotic porch pirate.

3D Printed Dubai Building Is World's Largest
'This thing will start at one end of ...a house and build it complete to the other end, following drawings only.'

Grow Plants On Moon Or Mars!
'In contrast to the airless desolation outside, the interior of this five-acre greenhouse was the one most desirable place to be.'

California Gets Shockwave Rider-Style Avoidance Zones
'It was cheaper to pay the refugees to go without up-to-the-minute equipment.'

Microbot Interstellar von Neumann Explorers
'Evidently they have never had a planet of their own...'

Hail SmartCan! Your Trash Bin Takes Itself Out
'...a waste can twenty feet away stirred into life.'

Finally! Microsoft Surface Neo And Surface Duo Implement Excellent Courier Idea
'Runcible, whose pages were thicker and more densely packed with computational machinery...'

Tap Strap 2 Now With Air Mouse
'He waved his hand and the circuit switched abruptly.'

More SF in the News Stories

More Beyond Technovelgy science news stories

Home | Glossary | Invention Timeline | Category | New | Contact Us | FAQ | Advertise |
Technovelgy.com - where science meets fiction™

Copyright© Technovelgy LLC; all rights reserved.