Researchers Create Bowls, Coils, Ripples Of Living Tissue
Living tissue in a variety of shapes can be created programmatically by UC San Francisco researchers.
(Shapes made of living tissue)
This image shows the shapes made of living tissue, engineered by the researchers. By patterning mechanically active mouse or human cells to thin layers of extracellular fibers, the researchers could create bowls, coils, and ripple shapes. (credit: Alex Hughes)
Many of the complex folded and curved shapes that form human tissues can now be programmatically recreated with very simple instructions, UC San Francisco (UCSF) bioengineers report December 28 in the journal Developmental Cell.
The researchers used 3D cell-patterning to shape active mouse and human embryonic cells into thin layers of extracellular matrix fibers (a structural material produced by human cells that make up our connective tissue) to create bowls, coils, and ripples out of living tissue. A web of these fibers folded themselves up in predictable ways, mimicking developmental processes in natural human body tissue.
The UCSF lab approach instead used a precision 3D cell-patterning technology called DNA-programmed assembly of cells (DPAC). It provides an initial template (pattern) for tissue to later develop in vitro (in a test tube or other lab container). That tissue automatically folds itself into complex shapes in ways that replicate how in vivo (body) tissues normally assemble themselves hierarchically during development.
“This approach could significantly improve the structure, maturation, and vascularization” of tissues in organoids” (miniature models of human parts, such as brains, used for drug testing) “and 3D-printed tissues in general,” the researchers note in the paper.
Science fiction author Arthur C. Clarke told us (and me, since I read this book when it came out) about this idea in 1972, in his still-current novel Rendezvous With Rama; he used a much more compact word - biot - to describe them:
...now life, with all its infinite possibilities, had come to Rama. If the biological robots were not living creatures, they were certainly very good imitations.
No one knew who invented the word "biot"; it seemed to come into instant use, by a kind of spontaneous generation.
(Read more about Clarke's biots)
The term was used to describe creations like the spider tripod robots that Rama seemed to spontaneously generate for self-cleaning whenever an energy source (a sun) became available.
Scroll down for more stories in the same category. (Story submitted 4/9/2018)
Follow this kind of news @Technovelgy.
| Email | RSS | Blog It | Stumble | del.icio.us | Digg | Reddit |
you like to contribute a story tip?
Get the URL of the story, and the related sf author, and add
Comment/Join discussion ( 0 )
Related News Stories -
New Lifelike Material Powered By Artificial Metabolism
'... The biological robots were not living creatures.' - Arthur C. Clarke, 1972.
DNA May Contain Malware
'You were told to embed the logical pathogen.' - A. Reynolds and S. Baxter, 2016.
GMO Houseplant Cleans Your Air
Removes compounds too small to be captured by a HEPA filter.
Oil from Algae - Can It Be Done?
'We dump everything that's waste into the tanks, pump the oil off the top.' - Hal Clement, 1950.
Technovelgy (that's tech-novel-gee!)
is devoted to the creative science inventions and ideas of sf authors. Look for
the Invention Category that interests
you, the Glossary, the Invention
Timeline, or see what's New.
Datagrid Model Generation Perfect For Eternal Cities Of Science Fiction
'... there was enough flexibility to allow for wide variation.
Kazahk Ironist Protester Arrested For Blank Sign Protest
'...a man carried a white rectangular sign, blank on both sides.'
Bitcoin Surges Again, To $7,000
'... electronic, private cash, unbacked by any government, untraceable, completely anonymous.'
China Develops Taste Testing Robots
'Install taste buds in the end of one tentacle...'
North Sea Stone Age Reconstruction And Philip K Dick
'Your Dip digs back into antiquity. Rome. Greece. Dust and old volumes.'
Tesla Robotaxis Will Automatically Recharge Themselves
'Then it appeared to make up its mind, and trundled over to a wall socket...'
New Lifelike Material Powered By Artificial Metabolism
'... The biological robots were not living creatures.'
Husqvarna Automower 435X AWD
'Gramp Stevens sat in a lawn chair, watching the mower at work...'
Elon Musk Foretells Tesla Sans Steering Wheel
'How about the steering wheel... I don't need one.'
Adversarial Patches Trick Computer Vision
'The surveillance cameras can all see it, but then they forget they’ve seen it.'
Amazon Warehouse Computer Can Fire People Now
'The system has already fired five people...'
BrainEx Restores Some Activity To Severed Pig Head
'... they placed the brain in a special solution, having all the properties of Nursing the brain cells.'
Yes, But Do Astrobees Have Lasers For Lightsaber Training?
'... Ancient weapons are no match for a good blaster at your side, kid.'
'Young Razorbacks Before Their Katanas Grow In'
'Twin robotic arms with gleaming three-foot sword blades unfolded from the forward hydraulic assemblies...'
A New Way To Run Into Things
'He made an adjustment, pointed the tube at the wall beside Etzwane, and projected a cone of light.'
'Metallic Wood' Strong Like Titanium, Floats In Water
'A metal... light as cork and stronger than steel...'
More SF in the News Stories
More Beyond Technovelgy science news stories