Researchers Create Bowls, Coils, Ripples Of Living Tissue
Living tissue in a variety of shapes can be created programmatically by UC San Francisco researchers.
(Shapes made of living tissue)
This image shows the shapes made of living tissue, engineered by the researchers. By patterning mechanically active mouse or human cells to thin layers of extracellular fibers, the researchers could create bowls, coils, and ripple shapes. (credit: Alex Hughes)
Many of the complex folded and curved shapes that form human tissues can now be programmatically recreated with very simple instructions, UC San Francisco (UCSF) bioengineers report December 28 in the journal Developmental Cell.
The researchers used 3D cell-patterning to shape active mouse and human embryonic cells into thin layers of extracellular matrix fibers (a structural material produced by human cells that make up our connective tissue) to create bowls, coils, and ripples out of living tissue. A web of these fibers folded themselves up in predictable ways, mimicking developmental processes in natural human body tissue.
The UCSF lab approach instead used a precision 3D cell-patterning technology called DNA-programmed assembly of cells (DPAC). It provides an initial template (pattern) for tissue to later develop in vitro (in a test tube or other lab container). That tissue automatically folds itself into complex shapes in ways that replicate how in vivo (body) tissues normally assemble themselves hierarchically during development.
“This approach could significantly improve the structure, maturation, and vascularization” of tissues in organoids” (miniature models of human parts, such as brains, used for drug testing) “and 3D-printed tissues in general,” the researchers note in the paper.
Science fiction author Arthur C. Clarke told us (and me, since I read this book when it came out) about this idea in 1972, in his still-current novel Rendezvous With Rama; he used a much more compact word - biot - to describe them:
...now life, with all its infinite possibilities, had come to Rama. If the biological robots were not living creatures, they were certainly very good imitations.
No one knew who invented the word "biot"; it seemed to come into instant use, by a kind of spontaneous generation.
(Read more about Clarke's biots)
The term was used to describe creations like the spider tripod robots that Rama seemed to spontaneously generate for self-cleaning whenever an energy source (a sun) became available.
Scroll down for more stories in the same category. (Story submitted 4/9/2018)
Follow this kind of news @Technovelgy.
| Email | RSS | Blog It | Stumble | del.icio.us | Digg | Reddit |
you like to contribute a story tip?
Get the URL of the story, and the related sf author, and add
Comment/Join discussion ( 0 )
Related News Stories -
DNA May Contain Malware
'You were told to embed the logical pathogen.' - A. Reynolds and S. Baxter, 2016.
GMO Houseplant Cleans Your Air
Removes compounds too small to be captured by a HEPA filter.
Oil from Algae - Can It Be Done?
'We dump everything that's waste into the tanks, pump the oil off the top.' - Hal Clement, 1950.
Amazing 'Hybrid' Solar-Powered Sea Slug Does Photosynthesis
Thank goodness for Star Trek.
Technovelgy (that's tech-novel-gee!)
is devoted to the creative science inventions and ideas of sf authors. Look for
the Invention Category that interests
you, the Glossary, the Invention
Timeline, or see what's New.
Unfurl The Future! Huawei Mate X versus Galaxy Fold
'A paper thin polycarbon screen unfurled silently from the top of the unit and immediately grew rigid.'
Amazon Echo And Google Home Should Have Morality Software
'The Dwoskin Morality Rating-Computer could 'spot the slightest tendency to deviation' from the social norm...'
China Building Robot Wives
'Want a life-companion, a pleasant one?'
China Social Credit System Like State-Run Whuffie
'At least there was no mandatory Whuffie check on the monorail platform...'
Project Soli Radar Gesture Chip Now FCC Approved
'He waved his hand and the circuit switched abruptly.'
Stan, Robot Valet, Will Drag Your Car Away
'He activated the grapple tracks. '
Jibo Home Robot Says Goodbye, Is Killswitched
'It resembles an oyster....'
Johns Hopkins Says Asteroid Deflection Will Be Difficult
'This obelisk is one huge deflector mechanism...'
Fabric Automatically Cools Or Insulates Based On Environment
'...a high-efficiency filter and heat-exchange system.'
Deepfakes From OpenAI GPT-2 Algorithm
'How can you compete with an IBM heavy-duty logomatic analogue?'
John Deere Self-Driving Tractor
'The huge plow... seemed to shake itself - and began to move back southward.'
North Focals Smart Glasses Provide Augmented Reality In Style
'The world ... is drenched in unfamiliar information all the way to the horizon.'
Tesla Driver Caught Napping Behind The Wheel
'Mary Risling settled back for a little nap...'
Hayabusa 2 To Begin Asteroid Mining
'We must dig down, and then doubtless we shall find the metal.'
Ionocraft Drone Powered By Electrohydrodynamic Thrust
'He saw one hiss by him as he rounded the corner, trailing a short whip antenna...'
Purdue Pharma Ready To Profit From OxyContin Use Or Addiction Recovery
'It may be organic damage. It may be permanent. Time'll tell, and only after you are off Substance D for a long while.'
More SF in the News Stories
More Beyond Technovelgy science news stories