Science Fiction
Dictionary
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
 |
Nanobees Sting Tumors With Melittin
Nanobees are nanoparticles laden with melittin, an ingredient in bee venom. Melittin is known to have therapeutic uses, but its use in medicine has been minimal due to the fact that it does damage to healthy cells as well. Researchers at Washington University in St. Louis came up with the nanobee idea as a way to get melittin directly to tumor cells.
(Nanobees with melittin sting cancer cells)
Among Dr. Soman's first experiments was to see how melittin interacted with the nanoparticles. He found that not only did it attach quickly to the outer, lipid layer of the nanoparticles, but that the attachment was stable, suggesting that the nanoparticle-melittin combination, or nanobee, might be able to circulate in the body and not attack healthy cells.The next issue was to figure out how to get the melittin, once it came upon a tumor, to detach from the nanoparticle and transfer to the cancer cells, taking its cell-killing properties with it. The researchers accomplished this by attaching a third component to the mix—a ligand, which is a chemical that binds two distinct compounds. The ligand they used in this case—which Dr. Schlesinger likens to a "molecular ZIP Code"—has an affinity for attaching to a receptor plentiful in newly formed blood vessels. That's useful in cancer treatment because tumors tend to form new blood vessels to feed themselves and grow.
In tests with mice, the nanobees slowed the growth of breast-cancer tumors significantly, shrank melanoma tumors and reduced precancerous lesions (compared with control groups).
These "nanobees" are yet another effort to find a way to deliver a measured quantity of agent to a very particular place in the body. When science fiction writers think about it, one way to solve this problem is to make a person very small. As in the sf classic Fantastic Voyage.
(Proteus from Fantastic Voyage)
Scroll down for more stories in the same category. (Story submitted 10/3/2009)
Follow this kind of news @Technovelgy.| Email | RSS | Blog It | Stumble | del.icio.us | Digg | Reddit |
Would
you like to contribute a story tip?
It's easy:
Get the URL of the story, and the related sf author, and add
it here.
Comment/Join discussion ( 0 )
Related News Stories - (" Medical ")
Bone-Building Drug Evenity Approved
'Compounds devised by the biochemists for the rapid building of bone...' - Edmond Hamilton, 1932.
BrainBridge Concept Transplant Of Human Head Proposed
'Briquet’s head seemed to think that to find and attach a new body to her head was as easy as to fit and sew a new dress.' - Alexander Belaev (1925)
Natural Gait With Prosthetic Connected To Nervous System
'The leg was to function, in a way, as a servo-mechanism operated by Larry’s brain...' - Charles Recour, 1949.
Brain Implant Is Able To Capture Your Inner Dialogue
'So you see, you can hide nothing from me.'
Technovelgy (that's tech-novel-gee!) is devoted to the creative science inventions and ideas of sf authors. Look for the Invention Category that interests you, the Glossary, the Invention Timeline, or see what's New.
Science Fiction
Timeline
1600-1899
1900-1939
1940's 1950's
1960's 1970's
1980's 1990's
2000's 2010's
Current News
Golf Ball Test Robot Wears Them Out
"The robot solemnly hit a ball against the wall, picked it up and teed it, hit it again, over and again...'
Boring Company Vegas Loop Like Asimov Said
'There was a wall ahead... It was riddled with holes that were the mouths of tunnels.'
Rigid Metallic Clothing From Science Fiction To You
'...support the interior human structure against Jupiter’s pull.'
Is The Seattle Ultrasonics C-200 A Heinlein Vibroblade?
'It ain't a vibroblade. It's steel. Messy.'
Roborock Saros Z70 Is A Robot Vacuum With An Arm
'Anything larger than a BB shot it picked up and placed in a tray...'
A Beautiful Visualization Of Compact Food
'The German chemists have discovered how to supply the needed elements in compact, undiluted form...'
Bone-Building Drug Evenity Approved
'Compounds devised by the biochemists for the rapid building of bone...'
Secret Kill Switch Found In Yutong Buses
'The car faltered as the external command came to brake...'
Inmotion Electric Unicycle In Combat
'It is about the size and shape of a kitchen stool, gyro-stabilized...'
Grok Scores Best In Psychological Tests
'Try to find out how he ticks...'
PaXini Supersensitive Robot Fingers
'My fingers are not that sensitive...'
Congress Considers Automatic Emergency Braking, One Hundred Years Too Late
'The greatest problem of all was the elimination of the human element of braking together with its inevitable time lag.'
The Desert Ship Sailed In Imagination
'Across the ancient sea floor a dozen tall, blue-sailed Martian sand ships floated, like blue smoke.'
The Zapata Air Scooter Would Be Great In A Science Fiction Story
'Betty's slapdash style.'
Thermostabilized Wet Meat Product (NASA Prototype)
There are no orbiting Michelin stars. Yet.
Could Crystal Batteries Generate Power For Centuries?
'Power could be compressed thus into an inch-square cube of what looked like blue-white ice'
