Spray-On Skin With Skin Cell Spray-Transplantation

Spray-on skin is under development at the University of Pittsburgh for use with burn victims. The mortality rate for victims suffering from full thickness -3rd degree- burns is high, due to the limits in availability of healthy skin cell area.


( Skin Cell Spray-Transplantation )

Biotechnology and tissue engineering methods lead to the use of skin cell cultures, taken from the patient’s healthy skin areas and expanded to cell sheets in Petri dishes. These methods, however, are not yet advanced enough to help in more severe cases. Pathophysiologic problems include serous fluid blisters between the transplanted tissue sheets and the wound and the subsequent loss of cell areas, non optimal cell nutrition in the early phase after cell transfer, water- and electrolyte dearrangements in the wound, toxin accumulation, and pH dearrangements.

The new skin cell transdermal spray technique developed by Jörg C. Gerlach, MD, PhD at Berlin University Hospital, Germany and at McGowan Institute for Regenerative Medicine, University of Pittsburgh can solve these problems.

Use of the connective tissue skin fibroblast cells additionally and in parallel to skin keratinocytes, allowing better tissue reorganization in the wound (cell biology approach).
Reduction of in vitro culture time to prevent differentiation of the basal keratinocytes in the in vitro phase. A faster and earlier therapy start is possible by islet-like distribution of single cells in the wound (cell application approach).
Application of the “tissue engineering in the wound“ approach, enabled by the use of a temporary hollow fiber membrane capillary bed, perfused with oxygenated nutrition and dialysis medium (wound healing approach), also allowing drug delivery supporting wound healing and antibiotic therapy to address infections. These capillaries are placed during the initial two days above the sprayed cells and below the wound dressing (biotechnology approach).

Science fiction fans were familiarized with the idea of spray-on skin in the works of Philip K. Dick. In his 1960 story Dr. Futurity, he wrote about art-derm:

Over her lacerated right shoulder he sprayed art-derm; it sealed off the open wound, halted bleeding, and prohibited infection.

Star Trek fans may recall the protoplaser used in the TNG episode Frame of Mind.

Via PTEI. Thanks also to Winchell Chung (aka @nyrath on Twitter).

Scroll down for more stories in the same category. (Story submitted 5/7/2010)

Follow this kind of news @Technovelgy.

| Email | RSS | Blog It | Stumble | del.icio.us | Digg | Reddit |

Would you like to contribute a story tip? It's easy:
Get the URL of the story, and the related sf author, and add it here.

Comment/Join discussion ( 1 )

Related News Stories - (" Medical ")

Biotech Firms Raised $Millions For Anti-Agathics (Longevity Drugs)
'Against Death doth no simple grow.' - James Blish, 1957.

Medical Tattoos Are STILL Being Researched
'Following the current craze, she has had a subdermal pattern of micro-channels implanted.'

Rise Of Skywalker Could Trigger Epileptic Seizures
'... then the screen started to flicker. I stared at it for a while.' - John Varley, 1984.

Injectable Magnetic Fluid Slows Bleeding, Aids Magneto
'There's something different about you.'

 

Google
  Web TechNovelgy.com   

Technovelgy (that's tech-novel-gee!) is devoted to the creative science inventions and ideas of sf authors. Look for the Invention Category that interests you, the Glossary, the Invention Timeline, or see what's New.

 

 

 

 

 

Current News

I Want My 1928 Telestereo Hologram Now
'Instantly there appeared standing upon the disk, the image of a man...'

Memes Now Come From Neural Nets
'Your order said for him to be able to be able to work out twists on the gags in the file...'

Robot Dog Learns To Be Doggy From Real Dogs
'So we took pictures of Guzub making a Three Planets, and I could construct this one to do it exactly right down to the thousandth of a second.'

Unwanted Cruise Ships Huddle Together Out At Sea
'On the screen they passed in an endless, boundaryless flood of green specks...'

Sono Sion Electric Car Charges As You Drive
'It drew its power from six square yards of sunpower screens on its low curved roof.'

News Mood Filter Web Extension
'He adjusted the n, the r and b knobs, and hopefully anticipated a turn for the better...'

Fetal Lamb Rests In Artificial Womb
'... stewing warm on their cushion of peritoneum and gorged with blood-surrogate and hormones, the foetuses grew and grew...'

MIT Wants To Catch Interstellar Visitors
'INVESTIGATE MYSTERIOUS OBJECT ENTERING NEW CALEDONIA SYSTEM FROM NORMAL SPACE'

AutoX Sets Up Asia's Largest Robotaxi Center
'The robot cab seemed to know where it was going and, no doubt, the master machine from which it received its signals knew.'

E - Ink's Automatic Self Styling Color-Changing Dress
'The racks of gowns itched and quivered, their colors running into blurred pools.'

Soft Robots Use Kirigami Piezoelectric Sensor Skin
'A worthy opponent was the golem.'

Bosch Smartglasses Laser Paints AR Image On Your Retina
'Soon we'll be testing a system that projects directly on the retina of the eye.'

Maybe We Could Hibernate Until The Covid-19 Pandemic's End
'Cold-rest was a common last resort therapy for functional psychoses.'

Workplace Monitoring Hell, I Mean, Tool For Safe Distancing
'And here is the weirdest part -- I never see another employee the entire day.'

Patent Office Says AIs Cannot Be Inventors
'The real smart ones are as smart as the Turing heat is willing to let 'em get.'

Starlink Orbital Network Like Coruscant Traffic Jam
Vermin of the Sky? Or Internet access for all?

More SF in the News Stories

More Beyond Technovelgy science news stories

Home | Glossary | Invention Timeline | Category | New | Contact Us | FAQ | Advertise |
Technovelgy.com - where science meets fiction™

Copyright© Technovelgy LLC; all rights reserved.