Anti-Viral Polymer Paints Flu Into A Corner

A remarkable anti-viral polymer can be applied like paint; it was developed by MIT's Alexander Klibanov. His intent is to develop a biocidal "paint" that can help reduce the spread of germs in public areas and hospitals.


(Bottom slide covered with alkylated PEI)

In the above illustration, a regular commercial glass slide (top) and another one coated with alkylated PEI "paint" (bottom) were sprayed with aqueous suspensions of Staphylococcus aureus cells, and then incubated. Some 200 bacterial colonies are seen on the unprotected slide—and only 4 on the protected one.

Staphylococcus aureus is described by the CDC as a "superbug" that is resistant to many types of antibiotics. Studies have shown that it can survive for weeks even on hard surfaces.

Klibanov writes:

Our recent studies have resulted in a new, “non-release” strategy for rendering common materials (plastics, glass, textiles) permanently microbicidal. This strategy, involving covalent attachment of certain long, moderately hydrophobic polycations to material surfaces, has been proven to be very effective against a variety of pathogenic bacteria and fungi, both airborne and waterborne. This work continues along with a quest for creating material coatings with anti-viral and anti-sporal activities.

Klibanov and his colleagues found that the prickly polymer worked on bacteria; they tested it with the smaller flu virus and found the same effects. They applied droplets of a flu solution to glass slips painted with the polymer. After a few minutes' exposure, they were unable to recover any active virus from the samples, meaning the coating reduced the pathogen's abundance by at least a factor of 10,000.

How does it work? In the case of bacteria, the polymer seems to gouge holes in a microbe's cell wall and spilling out its contents. The polymer molecules stay rigid because they are all positively charged and repel each other; they are like strands of hair standing on end from a static charge. The spikes have sufficiently few charges, however, that they can breach bacterial walls, which repel strongly charged molecules. The polymer probably neutralizes flu because the virus has an envelope around it suitable for spearing, Klibanov says.

Here are some other inventions that work on small organisms:

From Scientific American via MedGadget; read more about Alexander Klibanov.

Scroll down for more stories in the same category. (Story submitted 11/16/2006)

Follow this kind of news @Technovelgy.

| Email | RSS | Blog It | Stumble | del.icio.us | Digg | Reddit |

Would you like to contribute a story tip? It's easy:
Get the URL of the story, and the related sf author, and add it here.

Comment/Join discussion ( 0 )

Related News Stories - (" Medical ")

Purdue Pharma Ready To Profit From OxyContin Use Or Addiction Recovery
'It may be organic damage. It may be permanent. Time'll tell, and only after you are off Substance D for a long while.' - Philip K. Dick, 1977.

Organaut! Russians 3D Print Living Tissue In Space
'For a while your colonists will have to come up [to orbit] to the Hospital...' - Larry Niven, 1968.

MIT Scientists Create 'Peek-a-Boo Prober' From Jetsons
Well, George, it's the latest thing.

Wound Healing With Wearable Nanogenerators
'... forcing the energy transfer which allowed him to ... erase the other internal-external damage.' - Frank Herbert, 1972.

 

Google
  Web TechNovelgy.com   

Technovelgy (that's tech-novel-gee!) is devoted to the creative science inventions and ideas of sf authors. Look for the Invention Category that interests you, the Glossary, the Invention Timeline, or see what's New.

 

 

 

 

 

Current News

'Metallic Wood' Strong Like Titanium, Floats In Water
'A metal... light as cork and stronger than steel...'

Seabreacher, H.G. Winter's 1939 Torpoon
'Ken lay full-length in the padded body compartment, his feet resting on the controlling bars of the directional planes, hands on the torpoon's engine levers.'

Abundant Robotics Autonomous Apple Harvester Robot
'... little machines, that went from plant to plant... cutting off the ripe fruit.'

Charging An Electric Car In 2019 (Video), 1912 (Photo) And 1894 (Fiction)
'Recharge the batteries... in almost every town and village...'

Japan Uses Explosives On Asteroid
'...a tiny, rocket-powered projectile, drove towards the mysterious bulk. It hit, exploding into a cloud of incandescent vapour.'

Get Your Speeder Flying Motorcycle From Jetpack Aviation
'The flycycles were miracles of compact design.'

FLIR Black Hornet 3 Palm-sized Drone
These drones can provide situational awareness beyond visual line-of-sight capability.

Dockworkers Protest Driverless Trucks
'It resembled conventional human-operated transportation vehicles, but with one exception -- there was no driver's cabin.'

Flying Car Concept By Kash Sirinanda
'Each one consists of a hub with many tiny spokes... On the end is a squat foot, rubber tread on the bottom...'

Unfurl The Future! Huawei Mate X versus Galaxy Fold
'A paper thin polycarbon screen unfurled silently from the top of the unit and immediately grew rigid.'

Amazon Echo And Google Home Should Have Morality Software
'The Dwoskin Morality Rating-Computer could 'spot the slightest tendency to deviation' from the social norm...'

China Building Robot Wives
'Want a life-companion, a pleasant one?'

China Social Credit System Like State-Run Whuffie
'At least there was no mandatory Whuffie check on the monorail platform...'

Project Soli Radar Gesture Chip Now FCC Approved
'He waved his hand and the circuit switched abruptly.'

Stan, Robot Valet, Will Drag Your Car Away
'He activated the grapple tracks. '

Jibo Home Robot Says Goodbye, Is Killswitched
'It resembles an oyster....'

More SF in the News Stories

More Beyond Technovelgy science news stories

Home | Glossary | Invention Timeline | Category | New | Contact Us | FAQ | Advertise |
Technovelgy.com - where science meets fiction™

Copyright© Technovelgy LLC; all rights reserved.