Science Fiction
Dictionary
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
 |
E.T. Mouse Hearts Glow
Researchers at Cornell have created mice whose heart muscles have been genetically engineered to fluoresce when the muscles contract. Junichi Nakai of the RIKEN Brain Science Institute in Wako-shi, Japan, developed the fluorescent molecule by modifying a green fluorescent protein (derived from bioluminescent jellyfish) and making it glow brightly enough to be observed in the working heart. The sensor molecule turns on and off like a switch in the presence of calcium; calcium concentrations in the muscle increase with each muscle contraction.
(Mouse embryo heart fluoresces as it contracts with each beat)
In the graphic shown above, the heart of a mouse embryo goes from a resting state between beats (upper left) through upper heart chamber contraction, then finally lower heart chamber contraction (lower right).
Incredibly, in order to photograph a mouse heart beat (the mouse embryo's heart beats 6-10 times per second), a special camera cooled to -90 degrees Celsius is used to get a sharp image.
By the tenth day of development, a rudimentary heart is already beating, but it has only two chambers. The upper chamber contracts first, then the lower; this delay in contractions is obviously necessary for efficient pumping action. However, the atrio-ventricular node (AV node) does not develop until the thirteenth day; so, how does the heart function without it?
This technique allowed researchers to discover a layer of specialized cells on the surface of the developing heart that delays the beats between upper and lower chambers. These cells die off once the AV node has developed.
(E.T. and Elliot)
This isn't really a case in which science fiction has specifically anticipated a real scientific development, but I couldn't resist the story. In the movie E.T. the Extraterrestrial director Steven Spielberg shows E.T.'s heart glowing as he communicates with his fellows aboard their ship.
For more miraculous mice stories, read Lab Mice Unexpectedly Regenerate Limbs, Organs, Klotho Anti-Aging Mouse Gene and Yoda - The World's Oldest Mouse. Read more about mice with glowing hearts.
Scroll down for more stories in the same category. (Story submitted 3/10/2006)
Follow this kind of news @Technovelgy.| Email | RSS | Blog It | Stumble | del.icio.us | Digg | Reddit |
Would
you like to contribute a story tip?
It's easy:
Get the URL of the story, and the related sf author, and add
it here.
Comment/Join discussion ( 1 )
Related News Stories - (" Biology ")
Lunar Biorepository Proposed For Cryo-Preservation Of Earth Species
'...there was no one alive who had ever seen them. But they existed in the Life Bank.' - John Varley, 1977.
Let's Make Slaver Sunflowers! Engineering Plants To Reflect Light
'The mirror-blossom was a terrible weapon.' - Larry Niven, 1965.
Machete-Wielding Philodendron Isn't Going To Take It Anymore
'The tree ended its wild larruping, stood like a dreaming giant liable to wake into frenzy at any moment.' - Eric Frank Russell, 1943.
Tsunami Forecasts Improved By Ionosphere Signals
'Swifter than any tide could ebb, the water was receding from the shore.'
Technovelgy (that's tech-novel-gee!) is devoted to the creative science inventions and ideas of sf authors. Look for the Invention Category that interests you, the Glossary, the Invention Timeline, or see what's New.
Science Fiction
Timeline
1600-1899
1900-1939
1940's 1950's
1960's 1970's
1980's 1990's
2000's 2010's
Current News
Korean Exoskeleton Suit F1 Helps You Put It On
'Better late than never.'
Have AI Researchers Given Up On 'Bio-Babies'?
'You couldn't have the capstone without the pyramid to hold it up.'
Bunker Busters and Bore-Pellets
'The first revelation of the new Soviet bore-pellets.'
'Spikeless' Brand Swizzle Stick Detects Spiked Drinks
'the unobtrusive inspections with tiny remote-cast snoopers...'
Heart Patches Grown In The Lab Repair Hearts
I'm hoping that this procedure becomes a normal part of medical practice!
Humanoid Robots Spotted In Homes Performing Household Chores
'... nothing was perfected until M. Pantalon announced the completion of his automatic valet.'
Musk Proposes Sites For Martian Cities
'...its streets were of remarkable width, with few or no buildings so high as mosques, churches, State-offices, or palaces in Tellurian cities.'
Bambot Open Source Cheap Delivery Robot
'Not since the time he rewired the delivery robot...'
Robot Collective Acts Like A Smart Material
'...it was all composed of tiny, identical cubes, carefully laid to form a tilelike surface.'
Vipera Electric Skis From Frigid Dynamics
'JOAN strapped on her power-skis...'
Pixel Watch 'Loss of Pulse Detection' And Philip K. Dick
'He carried on his person a triggering mechanism sensitive to his heartbeat.'
Nuclear Plant Restarted To Power AI To Feed Us Dreams
'...Anything was possible in my imaginary environment.'
SpaceX's Starman Tesla Roadster In Space
'Somewhere in space, a chrome and blue automobile raced the green light of Earth.'
Pivotal Blackfly Electric Aircraft Lifts And Hovers
'That explains how it was so easy for me to remain motionless in midair...'
CORLEO Robotic Horse Concept Looks Ready To Ride
Imagine digging your heels in to a steam horse!
Who First Thought Of A Tin Foil Hat?
'We had discovered that metal was relatively impervious to the telepathic effect.'
