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"Poised between intransigent scepticism and uncritical credulity, it [science fiction] is par excellence the literature of the open mind."
- John Brunner

Hubrizine  
  A drug that brings about greater alertness and cheerfulness.  

"Hubrizine stimulates the anterior portion of the spetal region of the brain. Stimulation in that area, Mr. Rosen, will bring about greater alertness, plus cheerfulness and a belief that events will work out all right on their own. It compares to this setting on the Hammerstein Mood Organ." He passed me a small glossy folded printed piece of paper; I saw Hammerstein stop-setting indications on it. "But the effect of the drug is much more intense; as you know, the amplitude of affect-shock produced by the Mood Organ is severely limited by law."
From We Can Build You, by Philip K. Dick.
Published by Amazing Stories in 1972
Additional resources -

See also Allswell, a playfully-named compound from Neal Stephenson's 2008 novel Anathem.

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  More Ideas and Technology from We Can Build You
  More Ideas and Technology by Philip K. Dick
  Tech news articles related to We Can Build You
  Tech news articles related to works by Philip K. Dick

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