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"What has allowed so many Psychopathic Personalities to rise so high in corporations and government, is that they are so decisive. Unlike normal people, they are never filled with doubts, for the simple reason that they cannot care what happens next."
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This is a very early expression of this idea.
Jack Williamson had lots of fun with this idea in his 1932 classic story The Pygmy Planet:
Floating in the brilliant violet liquid that filled the crystal tube was a gray mass, wrinkled and corrugated. This was divided by deep clefts into right and left hemispheres, which, in turn were separated into larger upper and smaller lower segments. White filaments ran through the violet liquid from its base toward the three rings or bands of green metal that encircled the cylinder.
In an instant, Larry realized that the gray mass was a human brain. The larger, upper part the cerebrum, the smaller mass at the back the cerebellum. And the white filaments were nerves, by means of which this brain controlled its astounding, mechanical body!
A brain in a machine!
Hamilton reused this idea in The Face of the Deep (1942):
The Brain, third of the Futuremen, was by far the strangest. Yet he had been an ordinary human, once. He had been Simon Wright, brilliant, aging Earth scientist. Dying of an incurable ailment, Wright's living brain had been removed from his human body and transferred into a special serum case in which it still lived, thought and acted. The Brain now resembled a square box of transparent metal. Upon one face of it were his protruding lenslike eyes and microphonic ears and speech apparatus. From compact generators inside the case jetted the magnetic tractorbeams that enabled the Brain to glide swiftly through the air and to handle objects and tools.
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