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"You have to budget the number of fuzzy rules you use to control a system. It turns out, you can state the optimality principle in three words: 'patch the bumps.'"
- Bart Kosko

Genetic Engineering  
  Direct manipulation of genetic material  

Jack Williamson coined the term in this novel.

"Kendrew's process?" Dane whispered huskily. "Genetic engineering?"

"Kendrew?" Her blue eyes widened innocently. No, our process isn't genetic engineering..."

From Dragon's Island, by Jack Williamson.
Published by Not Known in 1951
Additional resources -

Compare to Mind Control Genetically Modified Food from Robert Heinlein's 1941 novel Methuselah's Children.

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Additional resources:
  More Ideas and Technology from Dragon's Island
  More Ideas and Technology by Jack Williamson
  Tech news articles related to Dragon's Island
  Tech news articles related to works by Jack Williamson

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