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"The answer to the problem of information overload on the Net is reputations… engineer a system called a reputation server."
- Neal Stephenson

Anti-Tri-D Shot  
  Counteracts the deadly pesticide Tri-D.  

They were simply injections that everyone had to receive at regular twenty-one-day intervals, to counteract the lethal effect of food, and the notable thing about them was the great importance of the twenty-one-day period. To miss one's Tri-D shot by as much as a couple of hours might mean serious consequences, even death... You can imagine the work it entailed for doctors in the United States, keeping the entire population protected against death by poisoning....
Technovelgy from The Morning of the Day They Did It, by E.B. White.
Published by The New Yorker Magazine in 1950
Additional resources -

Compare to young blood - new blood for old from Methuselah's Children (1941) by Robert Heinlein, the Sprung-Samser treatment from This Immortal (1966) by Roger Zelazny, conscious retarded animation from A Race Through Time (1933) by Donald Wandrei and the anti-agathic drugs from Cities in Flight (1957) by James Blish.

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Additional resources:
  More Ideas and Technology from The Morning of the Day They Did It
  More Ideas and Technology by E.B. White
  Tech news articles related to The Morning of the Day They Did It
  Tech news articles related to works by E.B. White

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